Monoamine Oxidase A peptide (141-154) (ab45814)

製品の概要

製品の詳細

  • 由来
    Synthetic
  • アミノ酸配列
    • 生物種
      Human
    • 配列
      DAPWEAQHADKWDK
    • 領域
      141 to 154

関連製品

特性

Our Abpromise guarantee covers the use of ab45814 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Blocking - Blocking peptide for Anti-Monoamine Oxidase A antibody (ab40835)

  • 製品の状態
    Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.

関連情報

  • 別名
    • Amine oxidase [flavin containing] A
    • Amine oxidase [flavin-containing] A
    • AOFA
    • AOFA_HUMAN
    • EC 1.4.3.4
    • MAO A
    • MAO-A
    • maoA
    • Monoamine oxidase A
    • Monoamine oxidase type A
    see all
  • 機能
    Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOA preferentially oxidizes biogenic amines such as 5-hydroxytryptamine (5-HT), norepinephrine and epinephrine.
  • 組織特異性
    Heart, liver, duodenum, blood vessels and kidney.
  • 関連疾患
    Defects in MAOA are the cause of Brunner syndrome (BRUNS) [MIM:300615]. Brunner syndrome is a form of X-linked non-dysmorphic mild mental retardation. Male patients are affected by a syndrome of borderline mental retardation and exhibit abnormal behavior, including disturbed regulation of impulsive aggression. Obligate female carriers have normal intelligence and behavior.
  • 配列類似性
    Belongs to the flavin monoamine oxidase family.
  • 細胞内局在
    Mitochondrion outer membrane.
  • Information by UniProt

画像

  • All lanes : Monoamine Oxidase A peptide (141-154) (ab45814) at 0.3 µg/ml

    Lane 1 : Human Heart Lysate
    Lane 2 : Human Heart Lysate with Immunising peptide

    Lysates/proteins at 35 µg per lane.

    Developed using the ECL technique

    Observed band size : 70 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 85 kDa (possible non-specific binding).

参考文献

ab45814 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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