製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to MNK1
  • アプリケーション
    適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Mouse, Human
    交差が予測される動物種: Rat
  • 免疫原

    Synthetic non-phosphopeptide derived from human MNK1 around the phosphorylation site of threonine 255 (L-T-TP-P-C).

  • ポジティブ・コントロール
    • 3T3 cell extracts.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab79365 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/1000. Detects a band of approximately 51 kDa (predicted molecular weight: 51 kDa).
ELISA 1/40000.

ターゲット情報

  • 機能
    May play a role in the response to environmental stress and cytokines. Appears to regulate transcription by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap.
  • 組織特異性
    Ubiquitous.
  • 配列類似性
    Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
    Contains 1 protein kinase domain.
  • 翻訳後修飾
    Dual phosphorylation of Thr-250 and Thr-255 activates the kinase. Phosphorylation of Thr-385 activates the kinase.
  • 細胞内局在
    Cytoplasm and Cytoplasm. Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • MAP kinase interacting kinase 1 antibody
    • MAP kinase interacting serine/threonine kinase 1 antibody
    • MAP kinase signal integrating kinase 1 antibody
    • MAP kinase signal-integrating kinase 1 antibody
    • MAP kinase-interacting serine/threonine-protein kinase 1 antibody
    • MAPK signal integrating kinase 1 antibody
    • MITOGEN-ACTIVATED PROTEIN KINASE-INTERACTING SERINE/THREONINE KINASE 1 antibody
    • mknk1 antibody
    • MKNK1_HUMAN antibody
    • MNK 1 antibody
    • Mnk1 antibody
    see all

画像

  • All lanes : Anti-MNK1 antibody (ab79365) at 1/500 dilution

    Lane 1 : 3T3 cell extracts
    Lane 2 : 3T3 cell extracts with immunising peptide at 10 µg

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 51 kDa
    Observed band size : 51 kDa
    Additional bands at : 27 kDa. We are unsure as to the identity of these extra bands.

プロトコール

参考文献

ab79365 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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