製品の概要

  • 製品名Anti-MNDA antibody
    MNDA 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal to MNDA
  • アプリケーション適用あり: IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Cynomolgus Monkey
  • 免疫原

    Synthetic peptide, corresponding to amino acids 311-408 of Human MNDA (NP_002423) with a proprietary tag.

  • ポジティブ・コントロール
    • Human kidney tissue

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab118371 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P Use a concentration of 3 µg/ml. Antigen retrieval is not essential but may optimise staining. Place sample in 1X citrate buffer (pH 6.0) in pressure cooker under 125oC for 4min and under 90oC for 45min.

ターゲット情報

  • 機能May act as a transcriptional activator/repressor in the myeloid lineage. Plays a role in the granulocyte/monocyte cell-specific response to interferon. Stimulates the DNA binding of the transcriptional repressor protein YY1.
  • 組織特異性Expressed constitutively in cells of the myeloid lineage. Found in promyelocyte stage cells as well as in all other stage cells including peripheral blood monocytes and granulocytes. Also appear in myeloblast cells in some cases of acute myeloid Leukemia.
  • 配列類似性Contains 1 DAPIN domain.
    Contains 1 HIN-200 domain.
  • ドメインIts N-terminal half (200 amino acids) is sufficient for maximum enhancement of YY1 DNA binding and a portion of this sequence is responsible for binding YY1.
  • 細胞内局在Nucleus. Cytoplasm. Uniformly distributed throughout the interphase cell nucleus. Associates with chromatin.
  • Information by UniProt
  • 参照データベース
  • 別名
    • MNDA antibody
    • MNDA_HUMAN antibody
    • Myeloid cell nuclear differentiation antigen antibody
    • OTTHUMP00000024384 antibody
    • PYHIN3 antibody
    see all

Anti-MNDA antibody 画像

  • Formalin-fixed, paraffin-embedded Human kidney tissue labelled with ab118371 at 3 µg/ml

Anti-MNDA antibody (ab118371) 使用論文

ab118371 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"