製品の概要

  • 製品名Anti-MMP9 antibody
    MMP9 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to MMP9
  • 特異性This antibody recognizes both native and reduced forms of MMP9. It does not cross react with other MMP family members (MMP1, MMP2, MMP3, etc).
  • アプリケーション適用あり: WB, Sandwich ELISAmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide based on the hinge region of the Human MMP9.

    (Peptide available as ab41069.)

  • ポジティブ・コントロール
    • WB: Human MMP9 and cell media from human chondrosarcoma.

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab38902 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use at an assay dependent dilution. Detects a band of approximately 92 kDa (predicted molecular weight: 78 kDa).
Sandwich ELISA Use a concentration of 0.5 µg/ml. Can be paired for Sandwich ELISA with Mouse monoclonal [SB15c] to MMP9 (ab51203). For sandwich ELISA, use this antibody as Detection at 0.5µg/ml with ab51203 as Capture.

ターゲット情報

  • 機能May play an essential role in local proteolysis of the extracellular matrix and in leukocyte migration. Could play a role in bone osteoclastic resorption. Cleaves KiSS1 at a Gly-
    -Leu bond. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments. Degrades fibronectin but not laminin or Pz-peptide.
  • 組織特異性Produced by normal alveolar macrophages and granulocytes.
  • 関連疾患Intervertebral disc disease
    Metaphyseal anadysplasia 2
  • 配列類似性Belongs to the peptidase M10A family.
    Contains 3 fibronectin type-II domains.
    Contains 4 hemopexin repeats.
  • ドメインThe conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.
  • 翻訳後修飾Processing of the precursor yields different active forms of 64, 67 and 82 kDa. Sequentially processing by MMP3 yields the 82 kDa matrix metalloproteinase-9.
    N- and O-glycosylated.
  • 細胞内局在Secreted, extracellular space, extracellular matrix.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 82 kDa matrix metalloproteinase-9 antibody
    • 92 kDa gelatinase antibody
    • 92 kDa type IV collagenase antibody
    • CLG 4B antibody
    • CLG4B antibody
    • Collagenase Type 4 beta antibody
    • Collagenase type IV 92 KD antibody
    • EC 3.4.24.35 antibody
    • Gelatinase 92 KD antibody
    • Gelatinase B antibody
    • Gelatinase beta antibody
    • GelatinaseB antibody
    • GELB antibody
    • Macrophage gelatinase antibody
    • MANDP2 antibody
    • Matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) antibody
    • Matrix Metalloproteinase 9 antibody
    • MMP 9 antibody
    • MMP-9 antibody
    • MMP9 antibody
    • MMP9_HUMAN antibody
    • Type V collagenase antibody
    see all

Anti-MMP9 antibody 画像

Anti-MMP9 antibody (ab38902) 使用論文

ab38902 has not yet been referenced specifically in any publications.

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Thank you for contacting us and for alerting us to the problem you are experiencing with our products. I am sorry to hear you have had difficulty obtaining satisfactory results from these MMP9 antibodies. We take product complaints very seriously, and...

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Thank you for your enquiry. The immunogen sequence used to raise ab35399 was LQGSEKGFQSRHLA; corresponding to amino acids 175-198 of Human TIMP1. The immunogen sequence used to raise ab38902 is confidential. However, if you provide me with the ...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"