製品の概要

  • 製品名
  • 製品の詳細
    Goat polyclonal to MMP7
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide:

    QKLYGKRSNSRKK

    , corresponding to C terminal amino acids 255/267 of Human MMP7

  • ポジティブ・コントロール
    • Human Breast lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab39984 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 0.03 - 0.1 µg/ml. Detects a band of approximately 28 kDa (predicted molecular weight: 30 kDa).

ターゲット情報

  • 機能
    Degrades casein, gelatins of types I, III, IV, and V, and fibronectin. Activates procollagenase.
  • 配列類似性
    Belongs to the peptidase M10A family.
  • ドメイン
    The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.
  • 細胞内局在
    Secreted > extracellular space > extracellular matrix.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Matrilysin antibody
    • Matrin antibody
    • Matrix Metalloproteinase 7 antibody
    • Matrix metalloproteinase-7 antibody
    • MMP 7 antibody
    • MMP-7 antibody
    • MMP7 antibody
    • MMP7_HUMAN antibody
    • MPSL1 antibody
    • PUMP 1 antibody
    • Pump 1 protease antibody
    • Pump-1 protease antibody
    • PUMP1 antibody
    • Uterine matrilysin antibody
    • Uterine metalloproteinase antibody
    see all

画像

  • Anti-MMP7 antibody (ab39984) at 0.03 µg/ml (for 1 hour) + Human Breast lysate in RIPA buffer at 35 µg
    Developed using the ECL technique

    Predicted band size : 30 kDa
    Observed band size : 28 kDa (why is the actual band size different from the predicted?)

プロトコール

参考文献

ab39984 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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