製品の概要

  • 製品名Anti-MMP3 antibody
    MMP3 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to MMP3
  • アプリケーション適用あり: IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant fragment, corresponding to amino acids 251 - 478 of Human MMP3.

  • ポジティブ・コントロール
    • Conditioned, serum free medium from TPA treated human Endometrial cells. Human placenta tissue.

アプリケーション

Our Abpromise guarantee covers the use of ab32607 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P
  • 追加情報IHC-P: 1/50 for 30 min at room temperature. Staining of formalin fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at room temperature for 20 min.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Can degrade fibronectin, laminin, gelatins of type I, III, IV, and V; collagens III, IV, X, and IX, and cartilage proteoglycans. Activates procollagenase.
    • 配列類似性Belongs to the peptidase M10A family.
      Contains 4 hemopexin-like domains.
    • ドメインThe conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.
    • 細胞内局在Secreted > extracellular space > extracellular matrix.
    • Information by UniProt
    • 参照データベース
    • 別名
      • CHDS6 antibody
      • Matrix metalloproteinase 3 antibody
      • Matrix metalloproteinase-3 antibody
      • MGC126102 antibody
      • MGC126103 antibody
      • MGC126104 antibody
      • MMP 3 antibody
      • MMP-3 antibody
      • MMP3 antibody
      • MMP3_HUMAN antibody
      • Proteoglycanase antibody
      • SL-1 antibody
      • SL1 antibody
      • STMY antibody
      • STMY1 antibody
      • STR1 antibody
      • Stromelysin 1 antibody
      • Stromelysin-1 antibody
      • Transin 1 antibody
      • Transin-1 antibody
      see all

    Anti-MMP3 antibody 画像

    • Ab32607, at a 1/50 dilution, staining MMP3 in formalin fixed paraffin embedded human placenta tissue by Immunohistochemistry.

    Anti-MMP3 antibody (ab32607) 使用論文

    This product has been referenced in:
    • Lee CW  et al. Nestin depletion induces melanoma matrix metalloproteinases and invasion. Lab Invest 94:1382-95 (2014). IF, IHC ; Mouse, Human . Read more (PubMed: 25365206) »
    • Järvinen TM  et al. Matrix metalloproteinases as mediators of tissue injury in different forms of cutaneous lupus erythematosus. Br J Dermatol 157:970-80 (2007). Read more (PubMed: 17854363) »

    See all 2 Publications for this product

    Product Wall

    Application Immunohistochemistry (Frozen sections)
    Sample Human Tissue sections (human fetal heart)
    Specification human fetal heart
    Fixative Paraformaldehyde
    Permeabilization Yes - 0.1% saponin in PBS
    Blocking step Serum as blocking agent for 45 minute(s) · Concentration: 10% · Temperature: 37°C
    Username

    Dr. Silvia Martin-Puig

    Verified customer

    投稿 Apr 06 2009

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"