製品の概要

  • 製品名Anti-MMP28 antibody
    MMP28 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal to MMP28
  • アプリケーション適用あり: WB, Sandwich ELISAmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant fragment: LARGGLQVEP YYPRSLQDWG GIPEEVSGAL PRPDGSIIFF RDDRYWRLDQ AKLQATTSGR WATELPWMGC WHANSGSALF , corresponding to amino acids 441-521 of Human MMP28

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab57724 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
Sandwich ELISA
  • 追加情報WB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Can degrade casein. Could play a role in tissues homeostasis and repair.
    • 組織特異性Expressed at high levels in testes and lung. Low levels are detected in kidney, pancreas and skin. Also expressed in fetal lung, brain, skeletal muscle and kidney. Expressed selectively in keratinocytesis. Widely expressed in several carcinomas as well. Is up-regulated in response to injury in the skin.
    • 配列類似性Belongs to the peptidase M10A family.
      Contains 4 hemopexin-like domains.
    • ドメインThe conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.
    • 翻訳後修飾The precursor is cleaved by a furin endopeptidase.
    • 細胞内局在Secreted > extracellular space > extracellular matrix.
    • Information by UniProt
    • 参照データベース
    • 別名
      • Epilysin antibody
      • Matrix metalloproteinase 28 antibody
      • Matrix metalloproteinase-28 antibody
      • MM 28 antibody
      • MM28 antibody
      • MMP 25 antibody
      • MMP 28 antibody
      • MMP-28 antibody
      • MMP25 antibody
      • MMP28 antibody
      • MMP28_HUMAN antibody
      see all

    Anti-MMP28 antibody 画像

    プロトコール

    Anti-MMP28 antibody (ab57724) 使用論文

    This product has been referenced in:
    • Slany A  et al. Cell characterization by proteome profiling applied to primary hepatocytes and hepatocyte cell lines Hep-G2 and Hep-3B. J Proteome Res 9:6-21 (2010). WB ; Human . Read more (PubMed: 19678649) »

    See 1 Publication for this product

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    There are currently no Abreviews or Questions for ab57724.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"