製品の概要

  • 製品名
    Anti-MMP25 antibody - C-terminal
    MMP25 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to MMP25 - C-terminal
  • アプリケーション
    適用あり: ELISA, WBmore details
  • 種交差性
    交差種: Mouse, Human
  • 免疫原

    Synthetic peptide from the C terminal region of human MMP25 conjugated to KLH

  • ポジティブ・コントロール
    • Mouse liver tissue and HL60 cell lysates.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab70881 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA 1/1000.
WB 1/100 - 1/500. Detects a band of approximately 63 kDa (predicted molecular weight: 63 kDa).

ターゲット情報

  • 機能
    May activate progelatinase A.
  • 組織特異性
    Expressed predominantly in leukocytes, lung and spleen. Expressed also in colon carcinoma, astrocytoma and glioblastomas.
  • 配列類似性
    Belongs to the peptidase M10A family.
    Contains 4 hemopexin repeats.
  • ドメイン
    The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.
  • 翻訳後修飾
    The precursor is cleaved by a furin endopeptidase.
  • 細胞内局在
    Cell membrane. Secreted, extracellular space, extracellular matrix.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Leukolysin antibody
    • matrix metallopeptidase 25 antibody
    • matrix metallopeptidase like 1 antibody
    • matrix metalloproteinase 20 antibody
    • Matrix Metalloproteinase 25 antibody
    • Matrix metalloproteinase 25 precursor antibody
    • Matrix metalloproteinase-25 antibody
    • Membrane type 6 Matrix Metalloproteinase antibody
    • Membrane type Matrix Metalloproteinase 6 antibody
    • Membrane-type matrix metalloproteinase 6 antibody
    • Membrane-type-6 matrix metalloproteinase antibody
    • MMP 25 antibody
    • MMP-25 antibody
    • MMP20 antibody
    • MMP20A antibody
    • MMP25 antibody
    • MMP25_HUMAN antibody
    • MMPL1 antibody
    • MT-MMP 6 antibody
    • MT6-MMP antibody
    • MT6MMP antibody
    • MTMMP6 antibody
    see all

画像

  • All lanes : Anti-MMP25 antibody - C-terminal (ab70881) at 1/100 dilution

    Lane 1 : Mouse liver tissue lysate
    Lane 2 : HL60 cell lysate

    Lysates/proteins at 12.5 µg per lane.


    Predicted band size : 63 kDa
    Observed band size : 63 kDa

プロトコール

参考文献

ab70881 has not yet been referenced specifically in any publications.

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