製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to MMP10
  • 特異性
    Detects endogenous levels of total MMP10 protein.
  • アプリケーション
    適用あり: ICC/IF, ELISA, Flow Cyt, IHC-Frmore details
  • 種交差性
    交差種: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide (Human) from an internal region of MMP10.

  • ポジティブ・コントロール
    • HepG2 cells.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab59437 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ICC/IF 1/500 - 1/1000.
ELISA 1/10000.
Flow Cyt Use at an assay dependent concentration. PubMed: 21133852ab171870-Rabbit polyclonal IgG, is suitable for use as an isotype control with this antibody.
IHC-Fr Use at an assay dependent concentration. PubMed: 21133852

ターゲット情報

  • 機能
    Can degrade fibronectin, gelatins of type I, III, IV, and V; weakly collagens III, IV, and V. Activates procollagenase.
  • 配列類似性
    Belongs to the peptidase M10A family.
    Contains 4 hemopexin-like domains.
  • ドメイン
    The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.
  • 細胞内局在
    Secreted > extracellular space > extracellular matrix.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Matrix metallopeptidase 10 (stromelysin 2) antibody
    • Matrix metalloprotease 10 antibody
    • Matrix metalloproteinase 10 (stromelysin 2) antibody
    • Matrix metalloproteinase 10 antibody
    • Matrix metalloproteinase-10 antibody
    • MMP 10 antibody
    • MMP-10 antibody
    • Mmp10 antibody
    • MMP10_HUMAN antibody
    • SL 2 antibody
    • SL-2 antibody
    • SL2 antibody
    • STMY 2 antibody
    • STMY2 antibody
    • Stromelysin 2 antibody
    • Stromelysin II antibody
    • Stromelysin-2 antibody
    • Stromelysin2 antibody
    • StromelysinII antibody
    • Transin 2 antibody
    • Transin-2 antibody
    • Transin2 antibody
    see all

Anti-MMP10 antibody 画像

  • Immunofluorescent analysis of MMP10 in HepG2 cells with ab59437 (1/500 dilution); in the presence or absence of immunizing peptide.

Anti-MMP10 antibody (ab59437) 使用論文

This product has been referenced in:
  • Clark RT  et al. T cell production of matrix metalloproteases and inhibition of parasite clearance by TIMP-1 during chronic Toxoplasma infection in the brain. ASN Neuro : (2010). Flow Cyt, IHC-Fr ; Mouse . Read more (PubMed: 21133852) »

See 1 Publication for this product

Product Wall

Application
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Sample
Human Tissue sections (First trimester decidua)
Antigen retrieval step
Heat mediated - Buffer/Enzyme Used: Sodium citrate
Permeabilization
Yes - 0.5% Triton
Specification
First trimester decidua
Blocking step
BSA as blocking agent for 30 minute(s) · Concentration: 5% · Temperature: 22°C
Fixative
Formaldehyde
Username

Ruhul Choudhury

Verified customer

投稿 Jan 25 2017

Thank you very much for your interest in Abcam and our products..

To our knowledge,the following antibodies you listed have not been tested in IHC-P. Tested applications and species are listed on the individual datasheets. These are updated ...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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