Anti-MLF1 Interacting Protein/PBIP1 抗体 (ab117078)


  • 製品名Anti-MLF1 Interacting Protein/PBIP1 antibody
    MLF1 Interacting Protein/PBIP1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to MLF1 Interacting Protein/PBIP1
  • アプリケーション適用あり: WB, IP, IHC-P, ICC/IFmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Cow, Dog, Chimpanzee
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to amino acids surrounding Thr78 of Human MLF1 Interacting Protein/PBIP1. The immunogen peptide is phosphorylated at Thr78.

  • ポジティブ・コントロール
    • Human Colon Adenocarcinoma tissue



Our Abpromise guarantee covers the use of ab117078 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/2000. Predicted molecular weight: 48 kDa.
IP Use at an assay dependent concentration.
IHC-P Use a concentration of 20 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
ICC/IF 1/100 - 1/500.


  • 機能Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. Plays an important role in the correct PLK1 localization to the mitotic kinetochores. A scaffold protein responsible for the initial recruitment and maintenance of the kinetochore PLK1 population until its degradation. Involved in transcriptional repression.
  • 組織特異性Expressed at high levels in the testis, fetal liver, thymus, bone marrow and at lower levels in the lymph nodes, placenta, colon and spleen. Present in all cell lines examined, including B-cells, T-cells, epithelial cells and fibroblast cells. Expressed at high levels in glioblastoma cell lines.
  • 翻訳後修飾Phosphorylated by PLK1 at Thr-78, creating a self-tethering site that specifically interacts with the polo-box domain of PLK1.
  • 細胞内局在Cytoplasm. Nucleus. Chromosome > centromere > kinetochore. Localizes in the kinetochore domain of centromeres. Colocalizes with PLK1 at the interzone between the inner and the outer kinetochore plates.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CENP U antibody
    • CENP-50 antibody
    • CENP-U antibody
    • CENP50 antibody
    • CENPU antibody
    • CENPU_HUMAN antibody
    • CENPU50 antibody
    • centromere protein of 50 kDa antibody
    • Centromere protein U antibody
    • FLJ23468 antibody
    • HHV8 LNAIP1 antibody
    • ICEN24 antibody
    • Interphase centromere complex protein 24 antibody
    • Kaposi Sarcoma Herpesvirus latent nuclear antigen interacting protein 1 antibody
    • KLIP-1 antibody
    • KLIP1 antibody
    • KSHV latent nuclear antigen interacting protein 1 antibody
    • KSHV latent nuclear antigen-interacting protein 1 antibody
    • KSHV LNAIP1 antibody
    • LNAIP 1 antibody
    • LNAIP-1 antibody
    • MLF1-interacting protein antibody
    • MLF1IP antibody
    • MLF1IP1 antibody
    • PBIP1 antibody
    • Polo-box-interacting protein 1 antibody
    see all

Anti-MLF1 Interacting Protein/PBIP1 antibody 画像

  • Human Colon Adenocarcinoma (formalin-fixed, paraffin-embedded) stained withab117078 at 20 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Anti-MLF1 Interacting Protein/PBIP1 antibody (ab117078) 使用論文

ab117078 has not yet been referenced specifically in any publications.

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