製品の概要

  • 製品名Mitomycin C (MMC)
  • 製品の詳細
    Anticancer and antibiotic agent
  • 別名
    • MMC
  • 生理活性の詳細

    Anticancer and antibiotic agent. Crosslinks DNA. Inhibits DNA synthesis and nuclear division. Also induces apoptosis.

  • 精製度> 99%

製品の特性

    アプリケーション

    Our Abpromise guarantee covers the use of ab120797 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    アプリケーション Abreviews 特記事項
    Functional Studies Use at an assay dependent concentration.

    Mitomycin C (MMC) 画像

    • Functional assays: Caspase 8 (active) FITC Staining Kit (ab65614)

      Active caspase 8 in control Jurkat cells (10e6/mL) or cells treated for five hours with 10 ug/mL Cyclohexamide (CHX) (ab120093) or four hours with 25 ug/mL Mitomycin C (MitoC) (ab120797). Background signal subtracted, duplicates; +/- SD.

    Mitomycin C (MMC) (ab120797) 使用論文

    This product has been referenced in:
    • Mladenov E  et al. Activation of the S phase DNA damage checkpoint by mitomycin C. J Cell Physiol 211:468-76 (2007). Read more (PubMed: 17167777) »
    • Park IC  et al. Mitomycin C induces apoptosis in a caspases-dependent and Fas/CD95-independent manner in human gastric adenocarcinoma cells. Cancer Lett 158:125-32 (2000). Read more (PubMed: 10960761) »
    • Sasaki M  et al. Re-evaluation of tumor-specific cytotoxicity of mitomycin C, bleomycin and peplomycin. Anticancer Res 26:3373-80 (0). Read more (PubMed: 17094455) »

    See 0 Publications for this product

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    There are currently no Abreviews or Questions for ab120797.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"