Mirtazapine, alpha2, 5-HT2, 5-HT3 antagonist (ab120068)
Key features and details
- Antidepressant. α2, 5-HT2, 5-HT3 antagonist.
- CAS Number: 85650-52-8
- Soluble in DMSO to 20 mM and in ethanol to 50 mM
- Form / State: Solid
- Source: Synthetic
製品の概要
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製品名
Mirtazapine, alpha2, 5-HT2, 5-HT3 antagonist -
製品の詳細
Antidepressant. α2, 5-HT2, 5-HT3 antagonist. -
別名
- 6-Azamianserin
- Org3770
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生理活性の詳細
Antagonist at α2, 5-HT2 and 5-HT3 receptors. Antidepressant in vivo.
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CAS 番号
85650-52-8 -
構造式
製品の特性
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体系名
1,2,3,4,10,14b-Hexahydro-2-methylpyrazino[2,1-a]pyrido[2,3-c]benzazepine -
分子量
265.35 -
分子式
C17H19N3 -
PubChem 登録番号
4205 -
保存方法
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解性
Soluble in DMSO to 20 mM and in ethanol to 50 mM -
使用に関する注意
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES 線形表記
CN1CC2N(CC1)c4ncccc4Cc3ccccc23 -
由来
Synthetic
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研究分野
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
参考文献 (2)
ab120068 は 2 報の論文で使用されています。
- Nerli E et al. In vitro modeling of dendritic atrophy in Rett syndrome: determinants for phenotypic drug screening in neurodevelopmental disorders. Sci Rep 10:2491 (2020). PubMed: 32051524
- Flores Gutiérrez J et al. Protective role of mirtazapine in adult female Mecp2+/- mice and patients with Rett syndrome. J Neurodev Disord 12:26 (2020). PubMed: 32988385