製品の概要

製品の詳細

  • 由来
    Synthetic

関連製品

特性

Our Abpromise guarantee covers the use of ab4981 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Blocking

  • 製品の状態
    Liquid
  • 備考


    This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product and rat Mint 3 protein, catalog ab3450. Using a solution of peptide of equal volume and concentration to the corresponding antibody will yield a large molar excess of peptide (~ 70-fold) for competitive inhibition of antibody-protein binding reactions.

  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

関連情報

  • 別名
    • Adapter protein X11gamma
    • amyloid beta (A4) precursor protein binding, family A, member 3
    • Amyloid beta A4 precursor protein-binding family A member 3
    • Amyloid beta precursor protein binding, family A, member 3 phosphotyrosine binding/ interacting domain (PTB) bearing protein
    • APBA3
    • APBA3_HUMAN
    • lin 10
    • MGC:15815
    • Mint 3
    • Mint-3
    • Neuron specific X11L2 protein
    • Neuron-specific X11L2 protein
    • Neuronal Munc18 1 interacting protein 3
    • Neuronal Munc18-1-interacting protein 3
    • phosphotyrosine binding/interacting domain (PTB) bearing protein
    • X11 like 2 protein 2
    • X11gamma
    • X11L2
    see all
  • 機能
    May modulate processing of the beta-amyloid precursor protein (APP) and hence formation of beta-APP. May enhance the activity of HIF1A in macrophages by inhibiting the activity of HIF1AN.
  • 組織特異性
    Expressed in all tissues examined with lower levels in brain and testis.
  • 配列類似性
    Contains 2 PDZ (DHR) domains.
    Contains 1 PID domain.
  • ドメイン
    Composed of an N-terminal domain, a middle phosphotyrosine-binding domain (PID/PTB) that mediates binding with the cytoplasmic domain of the beta-amyloid precursor protein, and two C-terminal PDZ domains thought to attach proteins to the plasma membrane.
  • 細胞内局在
    Cytoplasm > perinuclear region.
  • Information by UniProt

参考文献

ab4981 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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