製品の概要

  • 製品名
    Minocycline hydrochloride
  • 製品の詳細
    Antibiotic. Demonstrates multiple effects.
  • 生理活性の詳細
    Antibiotic. Demonstrates anti-inflammatory, antiapoptotic, antioxidant and neuroprotective effects. Blood-brain barrier permeable. Matrix metalloproteinase (MMP) inhibitor (IC50 = 290 μM at stromelysin (MMP-3).
  • 精製度
    > 99%

製品の特性

参考文献

This product has been referenced in:
  • Plane JM  et al. Prospects for minocycline neuroprotection. Arch Neurol 67:1442-8 (2010). Read more (PubMed: 20697034) »
  • Padi SS & Kulkarni SK Minocycline prevents the development of neuropathic pain, but not acute pain: possible anti-inflammatory and antioxidant mechanisms. Eur J Pharmacol 601:79-87 (2008). Read more (PubMed: 18952075) »
  • Gilbertson-Beadling S  et al. The tetracycline analogs minocycline and doxycycline inhibit angiogenesis in vitro by a non-metalloproteinase-dependent mechanism. Cancer Chemother Pharmacol 36:418-24 (1995). Read more (PubMed: 7543375) »

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