製品の概要

  • 製品名Anti-Milk Fat Globule 1 antibody [MFG-06]
    Milk Fat Globule 1 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [MFG-06] to Milk Fat Globule 1
  • 特異性Reacts with 40-45 kDa glycoprotein in human milk fat globule membrane preparation.
  • アプリケーション適用あり: IHC-P, WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Tissue, cells or virus corresponding to Human Human Milk Fat Globule 1. Tissue/ cell preparation (Human). Milk fat globule membrane preparation.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab2537 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P
WB
  • 追加情報IHC-P: Use at an assay dependant concentration. Strongly positive on human epithelia-based structures.
    WB: Use at an assay dependant concentration.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Plays an important role in the maintenance of intestinal epithelial homeostasis and the promotion of mucosal healing. Promotes VEGF-dependent neovascularization (By similarity). Contributes to phagocytic removal of apoptotic cells in many tissues. Specific ligand for the alpha-v/beta-3 and alpha-v/beta-5 receptors. Also binds to phosphatidylserine-enriched cell surfaces in a receptor-independent manner. Zona pellucida-binding protein which may play a role in gamete interaction. Binds specifically to rotavirus and inhibits its replication.
      Medin is the main constituent of aortic medial amyloid.
    • 組織特異性Mammary epithelial cell surfaces and aortic media. Overexpressed in several carcinomas.
    • 配列類似性Contains 1 EGF-like domain.
      Contains 2 F5/8 type C domains.
    • 翻訳後修飾Medin has a ragged N-terminus with minor species starting at Pro-264 and Gly-273.
    • 細胞内局在Membrane. Secreted.
    • Information by UniProt
    • 参照データベース
    • 別名
      • BA46 antibody
      • Breast epithelial antigen BA46 antibody
      • EDIL1 antibody
      • HMFG antibody
      • hP47 antibody
      • HsT19888 antibody
      • Lactadherin antibody
      • Medin antibody
      • MFG-E8 antibody
      • MFGE8 antibody
      • MFGM antibody
      • MFGM_HUMAN antibody
      • Milk fat globule EGF factor 8 antibody
      • Milk fat globule EGF factor 8 protein antibody
      • Milk fat globule-EGF factor 8 antibody
      • O acetyl disialoganglioside synthase antibody
      • OAcGD3S antibody
      • SED1 antibody
      • SPAG10 antibody
      • Sperm associated antigen 10 antibody
      • Sperm surface protein hP47 antibody
      see all

    Anti-Milk Fat Globule 1 antibody [MFG-06] (ab2537) 使用論文

    This product has been referenced in:
    • Bártková J  et al. Differentiation patterns of testicular germ-cell tumours as revealed by a panel of monoclonal antibodies. Tumour Biol 8:45-56 (1987). Read more (PubMed: 2440095) »

    See 1 Publication for this product

    Product Wall

    Nos anticorps anti hMFG1 sont des anticorps monoclonaux contre la protéine totale hMFG1, et nous ne savons pas ou se situe l'épitope. Cependant, j'ai effectué une recherche d'homologie entre les formes 1 et 8 et vous trouverez en attachement les résu...

    Read More

    Thank you for your enquiry and your patience. We do not know if it is due to glycosylation pattern of a single holoprotein or the antibody detects several proteins in that range. The WB image shows results in typical glycoprotein "smear" band of the in...

    Read More

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"