Anti-MHC class II RT Ib 抗体 [F17-23-2] (ab33745)

製品の概要

  • 製品名Anti-MHC class II RT Ib antibody [F17-23-2]
    MHC class II RT Ib 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [F17-23-2] to MHC class II RT Ib
  • 特異性Recognizes the rat RT1B MHC class II antigen, reacting with haplotypes a, l and n expressed on rat strains including DA, LEW, and BN.
  • アプリケーション適用あり: Flow Cyt, IHC-Frmore details
  • 種交差性
    交差種: Rat
  • 免疫原

    Partially purified MHC antigens (Rat)

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • バッファーPreservative: 0.09% Sodium Azide
    Constituents: 5-10% Foetal calf serum, PBS, 0.2M Tris HCl. pH 7.4
  • 精製度Tissue culture supernatant
  • ポリ/モノモノクローナル
  • クローン名F17-23-2
  • ミエローマNS1
  • アイソタイプIgG1
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab33745 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Flow Cyt
IHC-Fr
  • 追加情報Flow Cyt: Use 50µl of 1/5 diluted antibody sample for 106 cells in 100µl.
    IHC-Fr: Use at an assay dependent dilution.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 関連性Recognizes a polymorphic determinant on rat Ia present on Lewis, Wistar, and AO rat strains (although it is apparently expressed in lower amounts in AO rats) but not BN, DA, or PVG/c strains. Also cross-reacts with mouse strains (MHC haplotypes b and s ) and analysis of recombinant mouse strains shows that the determinant maps to the I-A region and correlates with mouse Ia specificity 9 (1). Ia antigens are recognized on approximately 18% of thymocytes but does not significantly label the majority of peripheral T lymphocytes (1,3,4). Thus, is particularly useful for distinguishing Ia positive cells from different rat strains and has been used in the recognition of cells of donor origin in bone marrow reconstituted radiation chimeras.
    • 細胞内局在Type I membrane protein.
    • 別名
      • major histocompatibility complex antibody
      • major histocompatibility complex class II antibody

    Anti-MHC class II RT Ib antibody [F17-23-2] (ab33745) 使用論文

    This product has been referenced in:
    • Mirenda V  et al. Modified dendritic cells coexpressing self and allogeneic major histocompatability complex molecules: an efficient way to induce indirect pathway regulation. J Am Soc Nephrol 15:987-97 (2004). Read more (PubMed: 15034101) »

    See 1 Publication for this product

    Product Wall

    Merci de votre appel de toutà l'heure.

    Voici les résultats du blast promises. Comme discuté au téléphone, nous avons aussi des anticorps contre le RT1 class Ib de rat directement, comme par exemple le ab3374...

    Read More

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"