Anti-MHC Class II IA + IE 抗体 [M5/114.15.2] (FITC) (ab93561)

製品の概要

  • 製品名
    Anti-MHC Class II IA + IE antibody [M5/114.15.2] (FITC)
    MHC Class II IA + IE 一次抗体 製品一覧
  • 製品の詳細
    Rat monoclonal [M5/114.15.2] to MHC Class II IA + IE (FITC)
  • 標識
    FITC. Ex: 493nm, Em: 528nm
  • 特異性
    ab93561 reacts with the mouse MHC Class II, both I-A and I-E subregion-encoded glycoproteins (I-Ab, I-Ad, I-Aq, I-Ed, I-Ek, not I-Af, I-Ak, or I-As). It detects a polymorphic determinant present on B cells, monocytes, macrophages, dendritic cells, and activated T lymphocytes from mice carrying the H-2b, H-2d, H-2q, H-2p, H-2r and H-2u but not from mice carrying the H-2s or H-2f haplotypes.
  • アプリケーション
    適用あり: Flow Cytmore details
  • 種交差性
    交差種: Mouse
  • 免疫原

    Tissue/ cell preparation (Mouse): Activated C57BL/6 mouse spleen cells.

  • ポジティブ・コントロール
    • Mouse C57BI/6 splenocytes
  • 特記事項

    The M5/114.15.2 antibody is reported to inhibit I-A-restricted T cell responses of the H-2b, H-2d, H-2q, H-2u but not H-2f, H-2k, or H-2s haplotypes.

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Store at +4°C.
  • バッファー
    pH: 7.20
    Preservative: 0.09% Sodium azide
    Constituents: 0.87% Sodium chloride, 0.16% Sodium phosphate, 0.1% Gelatin
  • Concentration information loading...
  • 精製度
    Protein G purified
  • 一次抗体 備考
    The M5/114.15.2 antibody is reported to inhibit I-A-restricted T cell responses of the H-2b, H-2d, H-2q, H-2u but not H-2f, H-2k, or H-2s haplotypes.
  • ポリ/モノ
    モノクローナル
  • クローン名
    M5/114.15.2
  • アイソタイプ
    IgG2b
  • 軽鎖の種類
    kappa
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab93561 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Flow Cyt Use at an assay dependent concentration.

ターゲット情報

  • 関連性
    The MHC Class II IA + IE molcules are expressed on antigen presenting cells (including B cells) and a subset of T cells from H-2 b, d, q, r bearing mice and are involved in antigen presentation to T cells expressing CD3/TCR and CD4 proteins.
  • 細胞内局在
    Single-pass type I membrane protein
  • 参照データベース
  • 別名
    • AI323765 antibody
    • E alpha f antibody
    • H 2Ea antibody
    • H 2I antibody
    • H2 Ea antibody
    • H2 I antibody
    • Histocompatibility 2, class II antigen E alpha antibody
    • I E alpha MHC class II antibody
    • Ia 3 antibody
    • Ia3 antibody
    • MGC117888 antibody
    • MHC class II antigen E alpha antibody
    • MHC class II protein antibody
    see all

プロトコール

参考文献

This product has been referenced in:
  • Zeng SL  et al. Mesenchymal stem cells abrogate experimental asthma by altering dendritic cell function. Mol Med Rep 12:2511-20 (2015). Read more (PubMed: 25936350) »
  • Unternaehrer JJ  et al. The tetraspanin CD9 mediates lateral association of MHC class II molecules on the dendritic cell surface. Proc Natl Acad Sci U S A 104:234-9 (2007). Read more (PubMed: 17190803) »

See all 7 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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