Anti-MHC class II I E kappa 抗体 [14-4-4S] (Biotin) (ab93504)

製品の概要

  • 製品名
    Anti-MHC class II I E kappa antibody [14-4-4S] (Biotin)
    MHC class II I E kappa 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [14-4-4S] to MHC class II I E kappa (Biotin)
  • 標識
    Biotin
  • 特異性
    ab93504 reacts with the mouse and rat MHC Class II, I-E subregion-encoded glycoprotein in mice strains of H-2k, H-2d, H-2p and H-2r. H-2f and H-2s haplotypes do not express the I-E antigen.
  • アプリケーション
    適用あり: Flow Cytmore details
  • 種交差性
    交差種: Mouse, Rat
  • 免疫原

    Tissue/ cell preparation: C3H mouse skin graft and splenocytes

  • ポジティブ・コントロール
    • Mouse splenocytes
  • 特記事項


    The 14-4-4S monoclonal antibody has been reported to block antigen presentation in in vitro assays.

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファー
    Preservative: 0.09% Sodium Azide
    Constituents: PBS, 150mM Sodium chloride, pH 7.2
  • Concentration information loading...
  • 精製度
    Protein G purified
  • 一次抗体 備考
    The 14-4-4S monoclonal antibody has been reported to block antigen presentation in in vitro assays.
  • ポリ/モノ
    モノクローナル
  • クローン名
    14-4-4S
  • アイソタイプ
    IgG2a
  • 軽鎖の種類
    kappa
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab93504 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Flow Cyt Use at an assay dependent concentration. ab18454-Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody.

ターゲット情報

  • 関連性
    A major histocompatibility complex class II receptor. These display processed antigens from virally infected or transformed cells. Class II positive cells ('antigen presenting cells') can take up antigens from outside by endocytosis, degrade them into small peptides, and re export the peptides (now bound to MHC class II protein) to the cell surface. These peptide MHC class II complexes can then be recognized by specific CD4+ lymphocytes.
  • 細胞内局在
    Type I membrane protein
  • 別名
    • H2 Ea antibody
    • H2-Ea antibody

プロトコール

Anti-MHC class II I E kappa antibody [14-4-4S] (Biotin) (ab93504) 使用論文

This product has been referenced in:
  • Spencer JS  et al. Expression and function of mixed isotype MHC class II molecules in normal mice. J Immunol 151:6822-32 (1993). Read more (PubMed: 8258692) »
  • Pruitt SK  et al. The effect of xenoreactive antibody and B cell depletion on hyperacute rejection of guinea pig-to-rat cardiac xenografts. Transplantation 56:1318-24 (1993). Read more (PubMed: 8278996) »

See all 4 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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