製品の概要

  • 製品名Anti-MHC class II I E kappa antibody [14-4-4S]
    MHC class II I E kappa 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [14-4-4S] to MHC class II I E kappa
  • 特異性This antibody is specific to an epitope on mouse I-E? MHC class II alloantigen. The antibody reacts with the I-E? class II alloantigen on cells from mice of the H-2d, H-2p, and H-2r haplotypes. The antibody has also been reported to cross react with the rat class II alloantigen RT1D.
  • アプリケーション適用あり: Functional Studies, Flow Cyt, IP, IHC-Fr, Blockingmore details
  • 種交差性
    交差種: Mouse
  • 免疫原

    Tissue/ cell preparation : C3H mouse skin graft and splenocytes.

  • 特記事項


製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファーpH: 8.20
    Constituent: 100% Borate buffered saline

    No preservatives or amine-containing buffer salts added.
  • Concentration information loading...
  • 精製度Protein A purified
  • ポリ/モノモノクローナル
  • クローン名14-4-4S
  • アイソタイプIgG2a
  • 軽鎖の種類kappa
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab25681 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Functional Studies Use at an assay dependent concentration.

In vitro induction of antigen specific B cell differentiation. Complement dependent cytotoxicity.

Flow Cyt Use at an assay dependent concentration. ab170191-Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody.
IP Use at an assay dependent concentration.
IHC-Fr Use at an assay dependent concentration.

Acetone fixed.

Blocking Use at an assay dependent concentration.

In vitro blocking of antigen presentation.

ターゲット情報

  • 関連性A major histocompatibility complex class II receptor. These display processed antigens from virally infected or transformed cells. Class II positive cells ('antigen presenting cells') can take up antigens from outside by endocytosis, degrade them into small peptides, and re export the peptides (now bound to MHC class II protein) to the cell surface. These peptide MHC class II complexes can then be recognized by specific CD4+ lymphocytes.
  • 細胞内局在Type I membrane protein
  • 別名
    • H2 Ea antibody
    • H2-Ea antibody

Anti-MHC class II I E kappa antibody [14-4-4S] (ab25681) 使用論文

This product has been referenced in:
  • Farr A  et al. Differential expression of CLIP:MHC class II and conventional endogenous peptide:MHC class II complexes by thymic epithelial cells and peripheral antigen-presenting cells. Eur J Immunol 26:3185-93 (1996). Read more (PubMed: 8977321) »
  • Roy M  et al. Studies on the interdependence of gp39 and B7 expression and function during antigen-specific immune responses. Eur J Immunol 25:596-603 (1995). Read more (PubMed: 7533092) »

See all 5 Publications for this product

Product Wall

There are currently no Abreviews or Questions for ab25681.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"