Mouse monoclonal [15-5-5.3] to MHC Class I H2 Dk (FITC)
標識FITC. Ex: 493nm, Em: 528nm
特異性MAb 15-5-5.3 reacts with the H2Dk class I alloantigen. It cross-reacts with H2Kd and with cells from mice with the H2f haplotype. The antibody does not react with other (e.g., a, b, p, q, r, s) haplotypes.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use 1µg for 106 cells. ab18455-Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody.
関連性MHC Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. MHC class I antigens are heterodimers consisting of one alpha chain (44kDa) with beta 2 microglobulin (11.5 kDa).