製品の概要

  • 製品名Anti-MHC Class I H2 Dd antibody [34-5-8S] (FITC)
    MHC Class I H2 Dd 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [34-5-8S] to MHC Class I H2 Dd (FITC)
  • 標識FITC. Ex: 493nm, Em: 528nm
  • 特異性Ab25057 reacts with a conformational epitope on H-2Dd MHC Class I found on the N-terminal domains of a1 and a2 chains when complexed with ß2-microglobulin. The antibody does not react with H-2Dd a chains synthesized in vitro. Weak cross-reactivity with cells from mice of the H-2b, H-2q, and H-2s haplotypes has been observed by flow cytometric analysis. Reactivity with cells from mice of the H-2f, H-2k, H-2p, and H-2r haplotypes has not been observed. Ab25057 has been reported to block the recognition of H-2Dd by Ly-49A+, Ly-49C+, and Ly-49G2+ natural killer cells.
  • アプリケーション適用あり: Flow Cytmore details
  • 種交差性
    交差種: Mouse
  • 免疫原

    Tissue/ cell preparation. (C57BL/6 x DBA/2)F1 hybrid mouse splenocytes.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C.
  • バッファーPreservative: 0.1% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 精製度Protein A purified
  • ポリ/モノモノクローナル
  • クローン名34-5-8S
  • アイソタイプIgG2a
  • 軽鎖の種類kappa
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab25057 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Flow Cyt Use 1µg for 106 cells. ab18455-Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody.

ターゲット情報

  • 関連性MHC Class I H2 Dd is involved in the presentation of foreign antigens to the immune system.
  • 細胞内局在Type I membrane protein.
  • 参照データベース
  • 別名
    • Class I major histocompatability complex antibody
    • H 2 class I histocompatibility antigen D D alpha chain antibody
    • H 2D antibody
    • H 2D cell surface glycoprotein antibody
    • H2 D antibody
    • H2 D(d) antibody
    • H2 D1 antibody
    • H2 DC1 beta transplantation antigen protein antibody
    • H2 L antibody
    • Histocompatibility 2 D region locus 1 antibody
    • MHC B7.2 antibody
    • MHC class I H2 antigen antibody
    • MHC class I heavy chain maturation peptide H 2D(d) antibody
    • MHC class I heavy chain maturation peptide H2 D(d) antibody
    • MHC class I heavy chain maturation peptide H2 Dd antibody
    • MHC class I polypeptide related sequence A antibody
    • MICA antibody
    • Q5k protein antibody
    see all

Anti-MHC Class I H2 Dd antibody [34-5-8S] (FITC) (ab25057) 使用論文

This product has been referenced in:
  • Coral S  et al. Epigenetic remodelling of gene expression profiles of neoplastic and normal tissues: immunotherapeutic implications. Br J Cancer 107:1116-24 (2012). Read more (PubMed: 22910318) »

See 1 Publication for this product

Product Wall

There are currently no Abreviews or Questions for ab25057.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"