FITC Anti-MHC class I 抗体 [34-1-2S] (ab95572)
Key features and details
- FITC Mouse monoclonal [34-1-2S] to MHC class I
- Suitable for: Flow Cyt
- Reacts with: Mouse
- Conjugation: FITC. Ex: 493nm, Em: 528nm
- Isotype: IgG2a
製品の概要
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製品名
FITC Anti-MHC class I antibody [34-1-2S]
MHC class I 一次抗体 製品一覧 -
製品の詳細
FITC Mouse monoclonal [34-1-2S] to MHC class I -
由来種
Mouse -
標識
FITC. Ex: 493nm, Em: 528nm -
特異性
ab95572 reacts with the mouse MHC class I, H-2Kd and H-2Dd. This cytotoxic antibody also cross reacts with K b,s,r,q,p -
アプリケーション
適用あり: Flow Cytmore details -
種交差性
交差種: Mouse -
免疫原
Tissue, cells or virus corresponding to Mouse MHC class I. C3H.SW Mouse splenocytes
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ポジティブ・コントロール
- Mouse splenocytes
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C. -
バッファー
pH: 7.20
Preservative: 0.09% Sodium azide
Constituents: 0.87% Sodium chloride, PBS -
Concentration information loading...
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精製度
Protein G purified -
ポリ/モノ
モノクローナル -
クローン名
34-1-2S -
アイソタイプ
IgG2a -
軽鎖の種類
kappa -
研究分野
関連製品
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Alternative Versions
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab95572の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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Flow Cyt |
Use 1µg for 105-8 cells.
Staining the cell sample in a final volume of 100 µL is recommended.
ab18455 - Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody.
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特記事項 |
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Flow Cyt
Use 1µg for 105-8 cells. Staining the cell sample in a final volume of 100 µL is recommended.
ab18455 - Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody.
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ターゲット情報
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関連性
MHC Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. MHC class I antigens are heterodimers consisting of one alpha chain (44kDa) with beta 2 microglobulin (11.5 kDa). The antigen is expressed by all somatic cells at varying levels. MHC Class I molecules are expressed on most nucleated cells where they present endogenously synthesized antigenic peptides to CD8+ T lymphocytes, which are usually cytotoxic T cells. Fibroblasts or neurons however only show a low level of antigen. -
細胞内局在
Cell Membrane; Type I membrane protein. -
別名
- A 28 antibody
- A 9 antibody
- Antigen presenting molecule antibody
see all
画像
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (3)
ab95572 は 3 報の論文で使用されています。
- Wu X et al. WEE1 inhibitor and ataxia telangiectasia and RAD3-related inhibitor trigger stimulator of interferon gene-dependent immune response and enhance tumor treatment efficacy through programmed death-ligand 1 blockade. Cancer Sci 112:4444-4456 (2021). PubMed: 34382294
- Bent EH et al. Microenvironmental IL-6 inhibits anti-cancer immune responses generated by cytotoxic chemotherapy. Nat Commun 12:6218 (2021). PubMed: 34711820
- Okazaki K et al. Enhancer remodeling promotes tumor-initiating activity in NRF2-activated non-small cell lung cancers. Nat Commun 11:5911 (2020). PubMed: 33219226