Anti-MHC Class 1 H2 Db 抗体 [27-11-13] (FITC) (ab25028)

製品の概要

  • 製品名
    Anti-MHC Class 1 H2 Db antibody [27-11-13] (FITC)
    MHC Class 1 H2 Db 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [27-11-13] to MHC Class 1 H2 Db (FITC)
  • 標識
    FITC. Ex: 493nm, Em: 528nm
  • 特異性
    ab25028 recognizes with the a3 domain of H-2Db class I MHC antigen. The antibody cross-reacts with the a3 domain of H-2Ld, H-2Dq and H-2Lq, but not H-2Kd or H-2Dd. Reactivity with haplotypes k, f, p, r, and s has not been observed.
  • アプリケーション
    適用あり: Flow Cyt, IHC-Fr, Functional Studiesmore details
  • 種交差性
    交差種: Mouse
  • 免疫原

    Mouse C3H.SW splenocytes

  • エピトープ
    An epitope on the a chain of H-2Db

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Store at +4°C.
  • バッファー
    Preservative: 0.1% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 精製度
    IgG fraction
  • ポリ/モノ
    モノクローナル
  • クローン名
    27-11-13
  • アイソタイプ
    IgG2a
  • 軽鎖の種類
    kappa
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab25028 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Flow Cyt Use 1µg for 106 cells. ab18455-Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody.
IHC-Fr Use at an assay dependent concentration.
Functional Studies Use at an assay dependent concentration. (Complement-dependent cytoxicity assay)

ターゲット情報

  • 関連性
    In the mouse the MHC Class 1 loci are called H2K, H2L and H2D. The equivalent loci in the human MHC are HLA (Human Leukocyte Antigen). MHC class I molecules are heterodimers, consisting of a single transmembrane polypeptide chain (the a-chain) which is highly polymorphic, and the invariant ß2 microglobulin (which is encoded elsewhere, not in the MHC). MHC class I molecules are found on almost every nucleated cell of the body. Their major function is to present peptide fragments derived from antigens to cytotoxic T cells.
  • 細胞内局在
    Cell Membrane; single pass type I membrane protein
  • 参照データベース
  • 別名
    • H 2D cell surface glycoprotein antibody
    • H2 class I histocompatibility antigen, DB alpha chain antibody
    • H2D(B) antibody
    • H2D1 antibody
    • Histocompatibility 2, D region locus 1 antibody
    see all

Anti-MHC Class 1 H2 Db antibody [27-11-13] (FITC) (ab25028) 使用論文

ab25028 has not yet been referenced specifically in any publications.

Product Wall

Both ab21321 and ab25028 recognize extracellular epitopes and can be used to stain live cells for FACS.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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