Anti-MHC Class 1 H2 Db 抗体 [27-11-13] (ab25244)

製品の概要

• 製品名Anti-MHC Class 1 H2 Db antibody [27-11-13]
  MHC Class 1 H2 Db 一次抗体 製品一覧
• 製品の詳細
  Mouse monoclonal [27-11-13] to MHC Class 1 H2 Db
• 特異性ab25244 recognizes the a3 domain of H2Db class I MHC antigen. The antibody cross-reacts with the a3 domain of H2Ld, H2Dq and H2Lq, but not H2Kd or H2Dd. Reactivity with haplotypes k, f, p, r, and s has not been observed.
• アプリケーション適用あり: Functional Studies, Flow Cyt, IHC-Frmore details
• 種交差性
  交差種: Mouse
  
• 免疫原

  C3H.SW splenocytes (Mouse)

• エピトープRecognizes an epitope on the a chain of H2Db.
• 特記事項

  
  

  ab25244 can be used for complement-dependent cytoxicity assays.

製品の特性

• 製品の状態Liquid
• 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• バッファーpH: 8.20
  Constituent: 100% Borate buffered saline
• Concentration information loading...
• 一次抗体 備考ab25244 can be used for complement-dependent cytoxicity assays.
• ポリ/モノモノクローナル
• クローン名27-11-13
• アイソタイプIgG2a
• 軽鎖の種類kappa
• 研究分野
  • Immunology
  • Adaptive Immunity
  • MHC
  • Class I

関連製品

• Compatible Secondaries
  • Goat Anti-Mouse IgG H&L (Alexa Fluor® 488) (ab150113)
  • Goat Anti-Mouse IgG H&L (HRP) (ab205719)

アプリケーション

ターゲット情報

• 関連性In the mouse the MHC Class 1 loci are called H2K, H2L and H2D. The equivalent loci in the human MHC are HLA (Human Leukocyte Antigen). MHC class I molecules are heterodimers, consisting of a single transmembrane polypeptide chain (the a-chain) which is highly polymorphic, and the invariant ß2 microglobulin (which is encoded elsewhere, not in the MHC). MHC class I molecules are found on almost every nucleated cell of the body. Their major function is to present peptide fragments derived from antigens to cytotoxic T cells.
• 細胞内局在Cell Membrane; single pass type I membrane protein
• 参照データベース
  • Entrez Gene: 14964 Mouse
  • SwissProt: P01899 Mouse
• 別名
  • H 2D cell surface glycoprotein antibody
  • H2 class I histocompatibility antigen, DB alpha chain antibody
  • H2D(B) antibody

  • H2D1 antibody
  • Histocompatibility 2, D region locus 1 antibody

  see all