製品の概要

  • 製品名Anti-MGMT antibody
    MGMT 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to MGMT
  • アプリケーション適用あり: WB, ICCmore details
  • 種交差性
    交差種: Rat, Human
    交差が予測される動物種: Mouse
  • 免疫原

    Synthetic peptide corresponding to an internal sequence of Human MGMT.

法規制情報

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab112504 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 22 kDa.
ICC Use a concentration of 1 µg/ml.

ターゲット情報

  • 機能Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
  • 配列類似性Belongs to the MGMT family.
  • 細胞内局在Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 6 O methylguanine DNA methyltransferase antibody
    • 6-O-methylguanine-DNA methyltransferase antibody
    • Agat antibody
    • AGT antibody
    • AI267024 antibody
    • EC 2.1.1.63 antibody
    • Methylated DNA protein cysteine methyltransferase antibody
    • Methylated-DNA--protein-cysteine methyltransferase antibody
    • Methylguanine DNA methyltransferase antibody
    • MGC107020 antibody
    • MGMT antibody
    • MGMT_HUMAN antibody
    • O 6 methylguanine DNA alkyltransferase antibody
    • O 6 methylguanine DNA methyltransferase antibody
    • O-6-methylguanine-DNA methyltransferase antibody
    • O-6-methylguanine-DNA-alkyltransferase antibody
    see all

Anti-MGMT antibody 画像

  • All lanes : Anti-MGMT antibody (ab112504)

    Lane 1 : Rat brain tissue lysate
    Lane 2 : Rat liver tissue lysate
    Lane 3 : Rat spleen tissue lysate
    Lane 4 : Rat thymus tissue lysate
    Lane 5 : MCF-7 whole cell lysate
    Lane 6 : HeLa whole cell lysate
    Lane 7 : Jurkat whole cell lysate
    Lane 8 : Raji whole cell lysate


    Predicted band size : 22 kDa
    Observed band size : 25 kDa (why is the actual band size different from the predicted?)
  • ab112504 staining MGMT in Lung cancer by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections).

Anti-MGMT antibody (ab112504) 使用論文

ab112504 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"