製品の概要

  • 製品名Anti-MFSD8 antibody
  • 製品の詳細
    Rabbit polyclonal to MFSD8
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog
  • 免疫原

    Synthetic peptide corresponding to a region within internal sequence amino acids 351-400 (FFILLPWGNQ FPKIQWEDLH NNSIPNTTFG EIIIGLWKSP MEDDNERPTG) of human MFSD8 (NP_689991).

  • ポジティブ・コントロール
    • HepG2 cell lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab108231 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 57 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能May be a carrier that transport small solutes by using chemiosmotic ion gradients.
  • 組織特異性Expressed at very low levels in all tissues tested.
  • 関連疾患Defects in MFSD8 are the cause of neuronal ceroid lipofuscinosis type 7 (CLN7) [MIM:610951]. A form of late infantile neuronal ceroid lipofuscinosis. CNL are a clinically and genetically heterogeneous group of neurodegenerative disorders characterized by the intracellular accumulation of autofluorescent lipopigment storage material in different patterns ultrastructurally. The patterns most often observed CLN7 are mixed combinations of granular, curvilinear, fingerprint, and rectilinear profiles. The clinical course includes progressive dementia, seizures, and progressive visual failure.
  • 配列類似性Belongs to the major facilitator superfamily.
  • 細胞内局在Lysosome membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Ceroid-lipofuscinosis neuronal protein 7 antibody
    • CLN7 antibody
    • Major facilitator superfamily domain-containing protein 8 antibody
    • MFSD8 antibody
    • MFSD8_HUMAN antibody
    see all

Anti-MFSD8 antibody 画像

  • Anti-MFSD8 antibody (ab108231) at 1 µg/ml + HepG2 cell lysate at 10 µg

    Predicted band size : 57 kDa

Anti-MFSD8 antibody (ab108231) 使用論文

ab108231 has not yet been referenced specifically in any publications.

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