製品の概要

  • 製品名Anti-Mesothelin antibody
    Mesothelin 一次抗体 製品一覧
  • 製品の詳細
    Chicken polyclonal to Mesothelin
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide, corresponding to amino acids 361-580 of Human Mesothelin

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab53285 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/2000. Detects a band of approximately 75 kDa (predicted molecular weight: 69 kDa).

ターゲット情報

  • 機能Membrane-anchored forms may play a role in cellular adhesion.
    Megakaryocyte-potentiating factor (MPF) potentiates megakaryocyte colony formation in vitro.
  • 組織特異性Expressed in lung. Expressed at low levels in heart, placenta and kidney. Expressed in mesothelial cells. Highly expressed in mesotheliomas, ovarian cancers, and some squamous cell carcinomas (at protein level).
  • 関連疾患Note=Antibodies against MSLN are detected in patients with mesothelioma and ovarian cancer.
  • 配列類似性Belongs to the mesothelin family.
  • 翻訳後修飾Both MPF and the cleaved form of mesothelin are N-glycosylated.
    Proteolytically cleaved by a furin-like convertase to generate megakaryocyte-potentiating factor (MPF), and the cleaved form of mesothelin.
  • 細胞内局在Secreted and Cell membrane. Golgi apparatus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CAK 1 antibody
    • CAK1 antibody
    • CAK1 antigen antibody
    • cleaved form antibody
    • Megakaryocyte potentiating factor antibody
    • Mesothelin antibody
    • Mesothelin isoform 1 precursor antibody
    • MPF antibody
    • Msln antibody
    • MSLN_HUMAN antibody
    • Pre pro megakaryocyte potentiating factor antibody
    • Pre-pro-megakaryocyte-potentiating factor antibody
    • SMR antibody
    • SMRP antibody
    • Soluble MPF mesothelin related protein antibody
    see all

Anti-Mesothelin antibody 画像

  • Anti-Mesothelin antibody (ab53285) at 1/2000 dilution + E coli-derived fusion protein

    Secondary
    Goat anti-IgY-HRP at 1/1000 dilution

    Predicted band size : 69 kDa
    Observed band size : 75 kDa (why is the actual band size different from the predicted?)

Anti-Mesothelin antibody (ab53285) 使用論文

ab53285 has not yet been referenced specifically in any publications.

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