製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to MERTK
  • 特異性
    This antibody detects a single 110 kDa MERTK protein in human RPE cell extracts. The antibody does not cross react with any other protein in RPE cells.
  • アプリケーション
    適用あり: WBmore details
    適用なし: IP
  • 種交差性
    交差種: Rat
    交差が予測される動物種: Mouse, Human
  • 免疫原

    Synthetic peptide corresponding to Rat MERTK aa 524-537.
    Sequence:

    VQETKFGGAFSEEDC

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab14920 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500. Predicted molecular weight: 110 kDa.
  • 追加情報
    Is unsuitable for IP.
  • ターゲット情報

    • 機能
      In case of filovirus infection, seems to function as a cell entry factor.
    • 組織特異性
      Not expressed in normal B- and T-lymphocytes but is expressed in numerous neoplastic B- and T-cell lines.
    • 関連疾患
      Defects in MERTK are the cause of retinitis pigmentosa type 38 (RP38) [MIM:613862]. RP38 is a retinal dystrophy belonging to the group of pigmentary retinopathies. Retinitis pigmentosa is characterized by retinal pigment deposits visible on fundus examination and primary loss of rod photoreceptor cells followed by secondary loss of cone photoreceptors. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well.
    • 配列類似性
      Belongs to the protein kinase superfamily. Tyr protein kinase family. AXL/UFO subfamily.
      Contains 2 fibronectin type-III domains.
      Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
      Contains 1 protein kinase domain.
    • 細胞内局在
      Membrane.
    • Information by UniProt
    • 参照データベース
    • 別名
      • c MER antibody
      • c mer proto oncogene tyrosine kinase antibody
      • c-mer antibody
      • cMER antibody
      • cmer protooncogene tyrosine kinase antibody
      • Eyk antibody
      • MER antibody
      • MER receptor tyrosine kinase antibody
      • MERK antibody
      • MERPEN antibody
      • Mertk antibody
      • MERTK c-mer proto-oncogene tyrosine kinase antibody
      • MERTK_HUMAN antibody
      • MGC133349 antibody
      • nmf12 antibody
      • Nyk antibody
      • Proto oncogene tyrosine protein kinase MER antibody
      • Proto oncogene tyrosine protein kinase MER precursor antibody
      • Proto-oncogene c-Mer antibody
      • Receptor tyrosine kinase MerTK antibody
      • RP38 antibody
      • STK kinase antibody
      • Tyrosine-protein kinase Mer antibody
      see all

    プロトコール

    Anti-MERTK antibody (ab14920) 使用論文

    ab14920 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab14920.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

    登録