製品の概要

  • 製品名Anti-MER + SKY antibody
  • 製品の詳細
    Rabbit polyclonal to MER + SKY
  • 特異性Detects endogenous levels of total MER + SKY protein.
  • アプリケーション適用あり: ELISA, WB, IHC-Pmore details
  • 種交差性
    交差種: Mouse, Human
    交差が予測される動物種: Rat
  • 免疫原

    Synthetic non-phosphopeptide derived from human MER + SKY around the phosphorylation site of tyrosine 749/681 (K-I-YP-S-G).

  • ポジティブ・コントロール
    • WB: extracts from 3T3 cells treated with EGF (200ng/ml, 5mins); IHC-P: Human brain tissue.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab79223 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA
WB
IHC-P
  • 追加情報ELISA: 1/5000.
    IHC-P: 1/50 - 1/100.
    WB: 1/500 - 1/1000. Predicted molecular weight: 110 or 97 kDa (MER and SKY respectively).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 関連性MER is a member of the MER/AXL/SKY receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP). SKY may be involved in cell adhesion processes, particularly in the central nervous system. In case of filovirus infection, seems to function as a cell entry factor.
    • 細胞内局在Membrane; Single-pass type I membrane protein
    • 参照データベース
    • 別名
      • AI323366 antibody
      • Brt antibody
      • Bruton agammaglobulinemia tyrosine kinase antibody
      • BYK antibody
      • c-mer antibody
      • c-mer proto-oncogene tyrosine kinase antibody
      • Dtk antibody
      • Etk 2 antibody
      • Eyk antibody
      • FLJ16467 antibody
      • Mer antibody
      • MER receptor tyrosine kinase antibody
      • MERTK antibody
      • MGC133349 antibody
      • Nyk antibody
      • OTTMUSP00000017810 antibody
      • rdy antibody
      • Receptor tyrosine kinase antibody
      • Receptor tyrosine kinase MerTK antibody
      • Receptor tyrosine tinase gene probably the gene for Rdy antibody
      • Retinal dystrophy antibody
      • RP23-30M20.1 antibody
      • RP23-356L21.1 antibody
      • RP38 antibody
      • RSE antibody
      • Sky antibody
      • STK kinase antibody
      • Tif antibody
      • TYRO3 antibody
      • TYRO3 protein tyrosine kinase 3 antibody
      • TYRO3 protein tyrosine kinase antibody
      • Tyrosine protein kinase byk antibody
      • Tyrosine protein kinase DTK antibody
      • Tyrosine protein kinase RSE antibody
      • Tyrosine protein kinase SKY antibody
      see all

    Anti-MER + SKY antibody 画像

    • Left panel: immunohistochemistry analysis of paraffin-embedded Human brain tissue using 1/50 ab79223. Right panel: same, after pre-incubation with the immunizing peptide.
    • All lanes : Anti-MER + SKY antibody (ab79223) at 1/500 dilution

      Lane 1 : 3T3 cell extract treated with EGF (200ng/ml, 5mins)
      Lane 2 : 3T3 cell extract treated with EGF (200ng/ml, 5mins) with immunizing peptide at 10 µg

      Lysates/proteins at 30 µg per lane.


      Predicted band size : 110 , 97 kDa
      Observed band size : 97 kDa (why is the actual band size different from the predicted?)
      Additional bands at : 120 kDa,150 kDa. We are unsure as to the identity of these extra bands.

    Anti-MER + SKY antibody (ab79223) 使用論文

    ab79223 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab79223.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"