製品の概要

  • 製品名Anti-Mephalan antibody [MP5/73]
  • 製品の詳細
    Rat monoclonal [MP5/73] to Mephalan
  • 特異性This antibody was developed to improve detection of melphalan-DNA adducts through its ability to recognise the stabilised adduct. This antibodiy can be used for quantification of melphalan adducts in purified DNA by ELISA and for immunofluorescent detection of melphalan-DNA adducts in single cells.
  • アプリケーション適用あり: ELISAmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Native DNA reacted with melphalan.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: None
    Constituents: PBS
  • Concentration information loading...
  • 精製度IgG fraction
  • ポリ/モノモノクローナル
  • クローン名MP5/73
  • ミエローマY3/Ag1.2.3
  • アイソタイプIgG2b
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab97892 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA Use at an assay dependent dilution.

ターゲット情報

  • 関連性Mephalan hydrochloride is a chemotherapy drug belonging to the class of nitrogen mustard alkylating agents.

Anti-Mephalan antibody [MP5/73] (ab97892) 使用論文

This product has been referenced in:
  • Rothbarth J  et al. Immunohistochemical detection of melphalan-DNA adducts in colon cancer cells in vitro and human colorectal liver tumours in vivo. Biochem Pharmacol 67:1771-8 (2004). Read more (PubMed: 15081876) »
  • Frank AJ & Tilby MJ Quantification of DNA adducts in individual cells by immunofluorescence: effects of variation in DNA conformation. Exp Cell Res 283:127-34 (2003). Read more (PubMed: 12581733) »

See all 3 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"