製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to MEMO1
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Zebrafish
  • 免疫原

    Synthetic peptide corresponding to a region within internal amino acids 143-192 (

    AMESHKDEFTIIPVLVGALSESKEQEFGKLFSKYLADPSNLFVVSSDFCH

    ) of Human MEMO1 (NP_057039).

  • ポジティブ・コントロール
    • Human fetal Heart Lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab98158 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 34 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能
    May control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton. Mediator of ERBB2 signaling. The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity. In turn, membrane-bound APC allows the localization of the MACF1 to the cell membrane, which is required for microtubule capture and stabilization. Is required for breast carcinoma cell migration.
  • 配列類似性
    Belongs to the MEMO1 family.
  • Information by UniProt
  • 参照データベース
  • 別名
    • C21orf19-like protein antibody
    • C2orf4 antibody
    • CGI 27 antibody
    • DKFZp434I0135 antibody
    • FLJ25031 antibody
    • HCV NS5A-transactivated protein 7 antibody
    • Hepatitis C virus NS5A-transactivated protein 7 antibody
    • Mediator of cell motility 1 antibody
    • Mediator of ErbB2-driven cell motility 1 antibody
    • MEMO antibody
    • Memo-1 antibody
    • memo1 antibody
    • MEMO1_HUMAN antibody
    • NS5ATP7 antibody
    • Protein MEMO1 antibody
    see all

画像

  • Anti-MEMO1 antibody (ab98158) at 1 µg/ml + Human fetal Heart Lysate at 10 µg

    Predicted band size : 34 kDa

プロトコール

参考文献

ab98158 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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