製品の概要

  • 製品名
    Memantine hydrochloride
  • 製品の詳細
    NMDA antagonist, ion channel site
  • 生理活性の詳細
    Antagonist at the NMDA receptor. Acts as a fast, voltage-dependent, open channel NMDA receptor blocker. Used in the clinic to treat Alzheimer's disease. Cognitive enhancer and anxiolytic in vivo.

    Also available in simple stock solutions (ab146687) - add 1 ml of water to get an exact, ready-to-use concentration.
  • 精製度
    > 98%

製品の特性

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  • Averaged time courses of NMDA receptor-isolated synaptic field potentials in dorsal lateral bed nucleus of the stria terminalis following 60 minutes of memantine (5 or 30 μM; ab120249) in naive adult male C57BL/6J mice.

参考文献

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