Anti-Melanopsin 抗体 (ab19383)
Key features and details
- Rabbit polyclonal to Melanopsin
- Suitable for: IHC-Fr, IHC-P, WB, ICC/IF
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
製品の概要
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製品名
Anti-Melanopsin antibody
Melanopsin 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to Melanopsin -
由来種
Rabbit -
アプリケーション
適用あり: IHC-Fr, IHC-P, WB, ICC/IFmore details -
種交差性
交差種: Mouse, Rat, Human -
免疫原
Synthetic peptide corresponding to Rat Melanopsin aa 455-474.
Sequence:EQKSKTPKTKRHLPSLDRRM
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
Preservative: 0.05% Sodium azide
Constituents: PBS, 0.1% BSA -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab19383の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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IHC-Fr |
Use at an assay dependent concentration.
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IHC-P |
Use at an assay dependent concentration.
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WB |
Use at an assay dependent concentration. Predicted molecular weight: 52 kDa.
Not recommended for the detection of endogenously expressed protein. |
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ICC/IF |
Use a concentration of 5 µg/ml.
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特記事項 |
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IHC-Fr
Use at an assay dependent concentration. |
IHC-P
Use at an assay dependent concentration. |
WB
Use at an assay dependent concentration. Predicted molecular weight: 52 kDa. Not recommended for the detection of endogenously expressed protein. |
ICC/IF
Use a concentration of 5 µg/ml. |
ターゲット情報
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機能
Photoreceptor required for regulation of circadian rhythm. Contributes to pupillar reflex and other non-image forming responses to light. May be able to isomerize covalently bound all-trans retinal back to 11-cis retinal. -
組織特異性
Eye. Expression is restricted within the ganglion and amacrine cell layers of the retina. -
配列類似性
Belongs to the G-protein coupled receptor 1 family. Opsin subfamily. -
細胞内局在
Cell membrane. Found in soma, dendrites and proximal part of axons of certain retinal ganglion cells. - Information by UniProt
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参照データベース
- Entrez Gene: 94233 Human
- Entrez Gene: 30044 Mouse
- Entrez Gene: 192223 Rat
- Omim: 606665 Human
- SwissProt: Q14D01 Human
- SwissProt: Q9UHM6 Human
- SwissProt: Q9QXZ9 Mouse
- SwissProt: Q8R456 Rat
see all -
別名
- Melanopsin antibody
- MGC142118 antibody
- MOP antibody
see all
データシートおよび資料
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Datasheet download
参考文献 (5)
ab19383 は 5 報の論文で使用されています。
- Kusumoto J et al. OPN4 belongs to the photosensitive system of the human skin. Genes Cells 25:215-225 (2020). PubMed: 31989708
- Yang K et al. Exposure to blue light stimulates the proangiogenic capability of exosomes derived from human umbilical cord mesenchymal stem cells. Stem Cell Res Ther 10:358 (2019). PubMed: 31779691
- Wang M et al. Nongenetic optical modulation of neural stem cell proliferation and neuronal/glial differentiation. Biomaterials 225:119539 (2019). PubMed: 31622821
- Diessler S et al. Rai1 frees mice from the repression of active wake behaviors by light. Elife 6:N/A (2017). PubMed: 28548639
- Man PS et al. Rhythmic expression of an egr-1 transgene in rats distinguishes two populations of photoreceptor cells in the retinal outer nuclear layer. Mol Vis 14:1176-86 (2008). IHC . PubMed: 18587494