Anti-MEK4/MKK4 抗体 [2D10D8,4G11B2] (ab60017)
Key features and details
- Mouse monoclonal [2D10D8,4G11B2] to MEK4/MKK4
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgM
製品の概要
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製品名
Anti-MEK4/MKK4 antibody [2D10D8,4G11B2]
MEK4/MKK4 一次抗体 製品一覧 -
製品の詳細
Mouse monoclonal [2D10D8,4G11B2] to MEK4/MKK4 -
由来種
Mouse -
アプリケーション
適用あり: IHC-Pmore details -
種交差性
交差種: Human -
免疫原
Recombinant full length protein corresponding to MEK4/MKK4.
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ポジティブ・コントロール
- IHC-P: Human thymoma tissue or human spleen tissue.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
バッファー
pH: 7.20
Constituent: PBS -
Concentration information loading...
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精製度
Protein A purified -
ポリ/モノ
モノクローナル -
クローン名
2D10D8,4G11B2 -
アイソタイプ
IgM -
研究分野
関連製品
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Compatible Secondaries
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab60017の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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IHC-P |
Use at an assay dependent concentration.
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特記事項 |
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IHC-P
Use at an assay dependent concentration. |
ターゲット情報
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機能
Dual specificity kinase that activates the JUN kinases MAPK8 (JNK1) and MAPK9 (JNK2) as well as MAPK14 (p38) but not MAPK1 (ERK2) or MAPK3 (ERK1). -
組織特異性
Abundant expression is seen in the skeletal muscle. It is also widely expressed in other tissues. -
配列類似性
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.
Contains 1 protein kinase domain. -
翻訳後修飾
Activated by phosphorylation on Ser/Thr by MAP kinase kinase kinases. - Information by UniProt
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参照データベース
- Entrez Gene: 6416 Human
- Omim: 601335 Human
- SwissProt: P45985 Human
- Unigene: 514681 Human
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別名
- c Jun N terminal kinase kinase 1 antibody
- C-JUN N-terminal kinase kinase 1 antibody
- Dual specificity mitogen activated protein kinase kinase 4 antibody
see all
画像
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Ab60017 (1:500) staining human MKK4 in lymphocyte of human thymoma tissue by immunohistochemistry using paraffin embedded tissue. Cytoplasmic localization is shown using DAB staining.
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Ab60017 (1:500) staining human MKK4 in human spleen tissue by immunohistochemistry using paraffin embedded tissue. Cytoplasmic localization is shown using DAB staining.
データシートおよび資料
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Datasheet download
参考文献 (0)
ab60017 は論文での使用が確認できていません。