製品の概要

  • 製品名Anti-MEIS1 antibody
    MEIS1 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to MEIS1
  • アプリケーション適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Cow
  • 免疫原

    Synthetic peptide:

    C-SEDITRSANLTDQ

    , corresponding to internal sequence amino acids 198 - 210 of Human MEIS1 (NP_002389.1)

  • ポジティブ・コントロール
    • Human Cerebral Cortex lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab80593 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
ELISA
  • 追加情報Peptide ELISA: antibody detection limit dilution 1/32000
    WB: Use at a concentration of 0.1 - 0.3 µg/ml. Predicted molecular weight: 43 kDa.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Acts as a transcriptional regulator of PAX6. Acts as a transcriptional activator of PF4 in complex with PBX1 or PBX2. Required for hematopoiesis, megakaryocyte lineage development and vascular patterning. May function as a cofactor for HOXA7 and HOXA9 in the induction of myeloid leukemias.
    • 組織特異性Expressed at low level in normal immunohepatopoietic tissues, including the fetal liver. Expressed in a subset of myeloid leukemia cell lines, with the highest expression seen in those with a megakaryocytic-erythroid phenotype. Also expressed at high levels in the cerebellum.
    • 関連疾患Defects in MEIS1 could be a cause of susceptibility to restless legs syndrome type 7 (RLS7) [MIM:612853]. Restless legs syndrome (RLS) is a neurologic sleep/wake disorder characterized by uncomfortable and unpleasant sensations in the legs that appear at rest, usually at night, inducing an irresistible desire to move the legs. The disorder results in nocturnal insomnia and chronic sleep deprivation.
    • 配列類似性Belongs to the TALE/MEIS homeobox family.
      Contains 1 homeobox DNA-binding domain.
    • 細胞内局在Nucleus.
    • Information by UniProt
    • 参照データベース
    • 別名
      • Homeo box protein Meis1 antibody
      • Homeobox protein Meis1 antibody
      • Leukemogenic homolog protein antibody
      • MEIS 1 antibody
      • Meis homeo box 1 antibody
      • Meis homeobox 1 antibody
      • Meis1 antibody
      • Meis1 mouse homolog antibody
      • Meis1 myeloid ecotropic viral integration site 1 homolog antibody
      • Meis1 myeloid ecotropic viral integration site 1 homolog mouse antibody
      • MEIS1 protein antibody
      • MEIS1_HUMAN antibody
      • MGC43380 antibody
      • Myeloid ecotropic viral integration site 1 homolog antibody
      • WUGSC:H NH0444B04.1 antibody
      see all

    Anti-MEIS1 antibody 画像

    • Anti-MEIS1 antibody (ab80593) at 0.1 µg/ml + Human Cerebral Cortex lysate (in RIPA buffer) at 35 µg

      Predicted band size : 43 kDa
      Observed band size : 43 kDa

    Anti-MEIS1 antibody (ab80593) 使用論文

    ab80593 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab80593.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"