製品の概要

  • 製品名
    Anti-MD2 antibody [4H1]
    MD2 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [4H1] to MD2
  • 特異性
    Reacts with both the monomeric and polymeric forms of soluble Human MD2 and the MD2/Toll-like receptor 4 complex. Able to inhibit LPS binding to MD2. It does not cross-react with Mouse MD2.
  • アプリケーション
    適用あり: WB, ELISA, Functional Studies, ICC/IFmore details
  • 種交差性
    交差種: Human
    非交差種: Mouse
  • 免疫原

    Baculovirally expressed His tagged Human MD2.

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファー
    Preservative: None
    Constituents: 0.1% BSA, PBS
  • Concentration information loading...
  • 精製度
    Protein G purified
  • 特記事項(精製)
    ab106132 was 0.2 µm filtered prior to formulation.
  • ポリ/モノ
    モノクローナル
  • クローン名
    4H1
  • アイソタイプ
    IgG1
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab106132 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/50. Predicted molecular weight: 19 kDa.
ELISA 1/50.
Functional Studies Use at an assay dependent dilution.
ICC/IF 1/50.

ターゲット情報

  • 機能
    Cooperates with TLR4 in the innate immune response to bacterial lipopolysaccharide (LPS), and with TLR2 in the response to cell wall components from Gram-positive and Gram-negative bacteria. Enhances TLR4-dependent activation of NF-kappa-B. Cells expressing both MD2 and TLR4, but not TLR4 alone, respond to LPS.
  • 翻訳後修飾
    N-glycosylated; high-mannose.
  • 細胞内局在
    Secreted > extracellular space.
  • Information by UniProt
  • 参照データベース
  • 別名
    • ESOP 1 antibody
    • ESOP-1 antibody
    • ESOP1 antibody
    • LY 96 antibody
    • Ly-96 antibody
    • LY96 antibody
    • LY96_HUMAN antibody
    • Lymphocyte antigen 96 antibody
    • md 2 antibody
    • MD 2 protein antibody
    • MD2 protein antibody
    • Myeloid differentiation protein 2 antibody
    • Protein MD 2 antibody
    • Protein MD-2 antibody
    • Protein MD2 antibody
    see all

参考文献

ab106132 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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