Anti-MCP4 抗体 [MM0137-3G14] (ab89453)

製品の概要

• 製品名
  Anti-MCP4 antibody [MM0137-3G14]
  MCP4 一次抗体 製品一覧
• 製品の詳細
  Mouse monoclonal [MM0137-3G14] to MCP4
• アプリケーション
  適用あり: Neutralising, Flow Cytmore details
• 種交差性
  交差種: Human
  
• 免疫原

  Recombinant Human MCP4.

製品の特性

• 製品の状態
  Liquid
• 保存方法
  Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• バッファー
  Preservative: None
  Constituents: PBS
• Concentration information loading...
• 精製度
  Protein G purified
• 特記事項（精製）
  IgG fraction of culture supernatant purified by Protein G affinity chromatography and 0.2 µm filtered.
• ポリ/モノ
  モノクローナル
• クローン名
  MM0137-3G14
• アイソタイプ
  IgG1
• 研究分野
  • Immunology
  • Innate Immunity
  • Macrophage / Inflamm.

  • Immunology
  • Innate Immunity
  • Chemokines
  • Beta Chemokines (CC)

関連製品

• Compatible Secondaries
  • Goat Anti-Mouse IgG H&L (Alexa Fluor® 488) (ab150113)
  • Goat Anti-Mouse IgG H&L (HRP) (ab205719)

アプリケーション

ターゲット情報

• 機能
  Chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils, but not neutrophils. Signals through CCR2B and CCR3 receptors. Plays a role in the accumulation of leukocytes at both sides of allergic and non-allergic inflammation. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. May play a role in the monocyte attraction in tissues chronically exposed to exogenous pathogens.
• 組織特異性
  Widely expressed. Found in small intestine, thymus, colon, lung, trachea, stomach and lymph node. Low levels seen in the pulmonary artery smooth muscle cells.
• 配列類似性
  Belongs to the intercrine beta (chemokine CC) family.
• 翻訳後修飾
  One major form (form long), and two minor forms (short chain and medium chain) are produced by differential signal peptide cleavage. The medium chain is about 30-fold less active than the long chain.
• 細胞内局在
  Secreted.

• Target information above from: UniProt accession Q99616 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• 参照データベース
  • Entrez Gene: 6357 Human
  • Omim: 601391 Human
  • SwissProt: Q99616 Human
  • Unigene: 414629 Human
• 別名
  • C-C motif chemokine 13 antibody
  • CCL13 antibody
  • CCL13_HUMAN antibody

  • Chemokine (C C motif) ligand 13 antibody
  • CK beta 10 antibody
  • CK-beta-10 antibody
  • CKb10 antibody
  • MCP-4 antibody
  • MGC17134 antibody
  • Monocyte chemoattractant protein 4 antibody
  • Monocyte chemotactic protein 4 antibody
  • NCC 1 antibody
  • NCC-1 antibody
  • NCC1 antibody
  • New CC chemokine 1 antibody
  • SCYA13 antibody
  • SCYL1 antibody
  • short chain antibody
  • Small inducible cytokine A13 precursor antibody
  • Small inducible cytokine subfamily A (Cys Cys) member 13 antibody
  • Small-inducible cytokine A13 antibody

  see all

プロトコール

• Flow cytometry protocols