製品の概要
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製品名Anti-MCP4 antibody [MM0137-3G14]
MCP4 一次抗体 製品一覧 -
製品の詳細Mouse monoclonal [MM0137-3G14] to MCP4
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由来種Mouse
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アプリケーション適用あり: Neutralising, Flow Cytmore details
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種交差性交差種: Human
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免疫原
Recombinant Human MCP4.
製品の特性
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製品の状態Liquid
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保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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バッファーPreservative: None
Constituents: PBS -
Concentration information loading... -
精製度Protein G purified
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特記事項（精製）IgG fraction of culture supernatant purified by Protein G affinity chromatography and 0.2 µm filtered.
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ポリ/モノモノクローナル
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クローン名MM0137-3G14
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アイソタイプIgG1
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研究分野
関連製品
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Compatible Secondaries
アプリケーション
Our Abpromise guarantee covers the use of ab89453 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| Neutralising | Use at an assay dependent concentration. | |
| Flow Cyt | 1/50 - 1/200. ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
|
ターゲット情報
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機能Chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils, but not neutrophils. Signals through CCR2B and CCR3 receptors. Plays a role in the accumulation of leukocytes at both sides of allergic and non-allergic inflammation. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. May play a role in the monocyte attraction in tissues chronically exposed to exogenous pathogens.
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組織特異性Widely expressed. Found in small intestine, thymus, colon, lung, trachea, stomach and lymph node. Low levels seen in the pulmonary artery smooth muscle cells.
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配列類似性Belongs to the intercrine beta (chemokine CC) family.
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翻訳後修飾One major form (form long), and two minor forms (short chain and medium chain) are produced by differential signal peptide cleavage. The medium chain is about 30-fold less active than the long chain.
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細胞内局在Secreted.
- Information by UniProt
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参照データベース
- Entrez Gene: 6357 Human
- Omim: 601391 Human
- SwissProt: Q99616 Human
- Unigene: 414629 Human
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別名
- C-C motif chemokine 13 antibody
- CCL13 antibody
- CCL13_HUMAN antibody
see all
プロトコール
参考文献
ab89453 has not yet been referenced specifically in any publications.
レビューと Q&A
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"