製品の概要

  • 製品名Anti-MCP4 antibody
    MCP4 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to MCP4
  • アプリケーション適用あり: Indirect ELISA, Sandwich ELISA, Neutralising, WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Highly pure (>98%) recombinant Human MCP4

製品の特性

  • 製品の状態Lyophilised:Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
  • 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • バッファーpH: 7.20
    Constituent: PBS
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab110609 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Indirect ELISA Use a concentration of 0.5 - 2 µg/ml. (using 100 µl/well antibody solution) allows the detection of at least 0.2 - 0.4 ng/well of recombinant Human MCP4.
Sandwich ELISA Use a concentration of 0.5 - 2 µg/ml. Can be paired for Sandwich ELISA with Rabbit polyclonal to MCP4 (Biotin) (ab83122). Using ab83122 as the detection antibody and ab110609 as the capture antibody, the detection limit for recombinant Human MCP4 is 0.2 - 0.4 ng/well, using 100 µl/well antibody solution.
Neutralising Use a concentration of 1 - 1.5 µg/ml. to yield one-half maximal inhibition [ND50] of the biological activity of MCP4 (30.0 ng/ml)
WB Use a concentration of 0.1 - 0.2 µg/ml. Predicted molecular weight: 11 kDa. The detection limit for recombinant Human MCP4 is 3.0 - 4.0 ng/lane, under either reducing or non-reducing conditions.

ターゲット情報

  • 機能Chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils, but not neutrophils. Signals through CCR2B and CCR3 receptors. Plays a role in the accumulation of leukocytes at both sides of allergic and non-allergic inflammation. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. May play a role in the monocyte attraction in tissues chronically exposed to exogenous pathogens.
  • 組織特異性Widely expressed. Found in small intestine, thymus, colon, lung, trachea, stomach and lymph node. Low levels seen in the pulmonary artery smooth muscle cells.
  • 配列類似性Belongs to the intercrine beta (chemokine CC) family.
  • 翻訳後修飾One major form (form long), and two minor forms (short chain and medium chain) are produced by differential signal peptide cleavage. The medium chain is about 30-fold less active than the long chain.
  • 細胞内局在Secreted.
  • Information by UniProt
  • 参照データベース
  • 別名
    • C-C motif chemokine 13 antibody
    • CCL13 antibody
    • CCL13_HUMAN antibody
    • Chemokine (C C motif) ligand 13 antibody
    • CK beta 10 antibody
    • CK-beta-10 antibody
    • CKb10 antibody
    • MCP-4 antibody
    • MGC17134 antibody
    • Monocyte chemoattractant protein 4 antibody
    • Monocyte chemotactic protein 4 antibody
    • NCC 1 antibody
    • NCC-1 antibody
    • NCC1 antibody
    • New CC chemokine 1 antibody
    • SCYA13 antibody
    • SCYL1 antibody
    • short chain antibody
    • Small inducible cytokine A13 precursor antibody
    • Small inducible cytokine subfamily A (Cys Cys) member 13 antibody
    • Small-inducible cytokine A13 antibody
    see all

Anti-MCP4 antibody (ab110609) 使用論文

ab110609 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"