製品の概要

  • 製品名Anti-MCP2 antibody
    MCP2 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to MCP2
  • アプリケーション適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide corresponding to a region within internal sequence amino acids 50-99 (SYTRITNIQC PKEAVIFKTK RGKEVCADPK ERWVRDSMKH LDQIFQNLKP) of human MCP2 (NP_005614).

  • ポジティブ・コントロール
    • Fetal heart lysate.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • 特記事項(精製)Purified by peptide affinity chromatography method.
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab83803 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 11 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
ELISA Use at an assay dependent concentration.

Titre using peptide based assay: 1/62500.

ターゲット情報

  • 機能Chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils. May play a role in neoplasia and inflammatory host responses. This protein can bind heparin. The processed form MCP-2(6-76) does not show monocyte chemotactic activity, but inhibits the chemotactic effect most predominantly of CCL7, and also of CCL2 and CCL5 and CCL8.
  • 組織特異性Highest expression found in the small intestine and peripheral blood cells. Intermediate levels seen in the heart, placenta, lung, skeletal muscle, thymus, colon, ovary, spinal cord and pancreas. Low levels seen in the brain, liver, spleen and prostate.
  • 配列類似性Belongs to the intercrine beta (chemokine CC) family.
  • 翻訳後修飾N-terminal processed form MCP-2(6-76) is produced by proteolytic cleavage after secretion from peripheral blood monocytes.
  • 細胞内局在Secreted.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Ccl8 antibody
    • CCL8_HUMAN antibody
    • HC14 antibody
    • MCP-2 antibody
    • MCP-2(6-76) antibody
    • Monocyte chemoattractant protein 2 antibody
    • Monocyte chemotactic protein 2 antibody
    • SCYA10 antibody
    • SCYA8 antibody
    • Small-inducible cytokine A8 antibody
    see all

Anti-MCP2 antibody 画像

  • Anti-MCP2 antibody (ab83803) at 1 µg/ml (in 5% skim milk / PBS buffer) + fetal heart lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 11 kDa
    Observed band size : 11 kDa
    Additional bands at : 42 kDa. We are unsure as to the identity of these extra bands.

Anti-MCP2 antibody (ab83803) 使用論文

ab83803 has not yet been referenced specifically in any publications.

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