製品の概要

  • 製品名Anti-MCM7 antibody
    MCM7 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to MCM7
  • アプリケーション適用あり: WBmore details
    適用なし: IP
  • 種交差性
    交差種: Mouse, Human
    交差が予測される動物種: Rabbit, Guinea pig, Chimpanzee, Rhesus monkey, Gorilla, Orangutan
  • 免疫原

    Synthetic peptide from within amino acids 669-719 of MCM7 (NP_005907.3)

  • ポジティブ・コントロール
    • HeLa, 293T, NIH 3T3 cell lysates.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファーPreservative: 0.09% Sodium Azide
    Constituents: Tris citrate/phosphate, pH 7 - 8
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab92385 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
  • 追加情報WB: 1/2000 - 1/10000. Predicted molecular weight: 81 kDa.

    Is unsuitable for IP.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for S-phase checkpoint activation upon UV-induced damage.
    • 配列類似性Belongs to the MCM family.
      Contains 1 MCM domain.
    • 翻訳後修飾Phosphorylated upon DNA damage, probably by ATM or ATR.
    • 細胞内局在Nucleus.
    • Information by UniProt
    • 参照データベース
    • 別名
      • CDABP0042 antibody
      • CDC 47 antibody
      • CDC47 antibody
      • CDC47 homolog antibody
      • Cdc47, S. cerevisiae, homolog of antibody
      • DNA replication licensing factor MCM7 antibody
      • Homolog of S. cerevisiae Cdc47 antibody
      • MCM 2 antibody
      • MCM 7 antibody
      • MCM2 antibody
      • MCM2, formerly antibody
      • Mcm7 antibody
      • MCM7 minichromosome maintenance deficient 7 antibody
      • MCM7_HUMAN antibody
      • Minichromosome Maintainence 7 antibody
      • Minichromosome maintainence, S. cerevisiae, homolog of antibody
      • Minichromosome maintenance complex component 7 antibody
      • Minichromosome maintenance deficient 7 antibody
      • Minichromosome maintenance protein 7 antibody
      • P1.1 MCM3 antibody
      • P1.1-MCM3 antibody
      • P1CDC47 antibody
      • P85MCM antibody
      • PNAS 146 antibody
      • PNAS146 antibody
      see all

    Anti-MCM7 antibody 画像

    • All lanes : Anti-MCM7 antibody (ab92385) at 0.4 µg/ml

      Lane 1 : HeLa whole cell lysate at 50 µg
      Lane 2 : HeLa whole cell lysate at 15 µg
      Lane 3 : HeLa whole cell lysate at 5 µg
      Lane 4 : 293T whole cell lysate at 50 µg
      Lane 5 : NIH3T3 whole cell lysate at 50 µg

      Developed using the ECL technique

      Predicted band size : 81 kDa


      Exposure time : 3 minutes

    Anti-MCM7 antibody (ab92385) 使用論文

    ab92385 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab92385.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"