製品の概要

  • 製品名
    Anti-MCF2 antibody
  • 製品の詳細
    Rabbit polyclonal to MCF2
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    KLH conjugated synthetic peptide between 803-833 amino acids from the C-terminal region of Human MCF2 (NP_001165347.1 , NP_001165348.1 , NP_001165350.1 , NP_005360.3 ,NP_001093325.1 , NP_001165349.1).

  • ポジティブ・コントロール
    • K562 cell line lysates

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab112588 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/100 - 1/500. Predicted molecular weight: 108 kDa.

ターゲット情報

  • 関連性
    Guanine nucleotide exchange factor (GEF) that modulates the Rho family of GTPases. Promotes the conversion of some member of the Rho family GTPase from the GDP-bound to the GTP-bound form. Isoform 1 exhibits no activity toward RHOA, RAC1 or CDC42. Isoform 2 exhibits decreased GEF activity toward CDC42. Isoform 3 exhibits a weak but significant activity toward RAC1 and CDC42. Isoform 4 exhibits significant activity toward RHOA and CDC42. The truncated DBL oncogene is active toward RHOA, RAC1 and CDC42.
  • 細胞内局在
    Cytoplasm Isoform 1: Membrane Isoform 3: Membrane. Note: Colocalizes with CDC42 to plasma membrane.
  • 参照データベース
  • 別名
    • DBL antibody
    • DBL-transforming protein antibody
    • MCF2 antibody
    • MCF2-transforming protein antibody
    • Proto-oncogene DBL antibody
    • Proto-oncogene MCF-2 antibody
    see all

画像

  • Anti-MCF2 antibody (ab112588) at 1/100 dilution + K562 cell line lysate at 35 µg

    Predicted band size : 108 kDa

プロトコール

参考文献

ab112588 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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