Anti-MC2 receptor 抗体 (ab77347)

製品の概要

  • 製品名
    Anti-MC2 receptor antibody
    MC2 receptor 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to MC2 receptor
  • アプリケーション
    適用あり: ELISA, WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Sheep, Horse, Cow, Dog, Chimpanzee
  • 免疫原

    Synthetic peptide:

    ENINNTARNNSDC

    , corresponding to N terminal amino acids 9-21 of Human MC2 receptor (NP_000520.1)

  • ポジティブ・コントロール
    • Human skin lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab77347 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA
WB
  • 追加情報
    Peptide ELISA: Antibody detection limit dilution: 1/32000.
    WB: Use at a concentration of 1 - 3 µg/ml. Detects a band of approximately 40 kDa (predicted molecular weight: 34 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能
      Receptor for ACTH. This receptor is mediated by G proteins (G(s)) which activate adenylate cyclase.
    • 組織特異性
      Melanocytes and corticoadrenal tissue.
    • 関連疾患
      Defects in MC2R are the cause of glucocorticoid deficiency type 1 (GCCD1) [MIM:202200]; also known as familial glucocorticoid deficiency type 1 (FGD1). GCCD1 is an autosomal recessive disorder due to congenital insensitivity or resistance to adrenocorticotropin (ACTH). It is characterized by progressive primary adrenal insufficiency, without mineralocorticoid deficiency.
    • 配列類似性
      Belongs to the G-protein coupled receptor 1 family.
    • 細胞内局在
      Cell membrane.
    • Information by UniProt
    • 参照データベース
    • 別名
      • ACTH receptor antibody
      • ACTH-R antibody
      • ACTHR antibody
      • ACTHR_HUMAN antibody
      • Adrenocorticotropic hormone receptor antibody
      • Adrenocorticotropin receptor antibody
      • Corticotropin receptor antibody
      • MC2 receptor antibody
      • MC2-R antibody
      • MC2R antibody
      • Melanocortin 2 receptor (adrenocorticotropic hormone) antibody
      • Melanocortin 2 receptor antibody
      • Melanocortin receptor 2 antibody
      see all

    Anti-MC2 receptor antibody 画像

    プロトコール

    Anti-MC2 receptor antibody (ab77347) 使用論文

    ab77347 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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