1/500 - 1/1000. Antigen retrieval is not essential but may optimise staining.
追加情報Is unsuitable for Flow Cyt,ICC or IP.
機能Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.
組織特異性Melanocytes and corticoadrenal tissue.
関連疾患Genetic variations in MC1R are a cause of susceptibility to cutaneous malignant melanoma type 5 (CMM5) [MIM:613099]. Malignant melanoma is a malignant neoplasm of melanocytes, arising de novo or from a pre-existing benign nevus, which occurs most often in the skin but also may involve other sites.
配列類似性Belongs to the G-protein coupled receptor 1 family.