Anti-MBD5 抗体 (ab103144)
Key features and details
- Rabbit polyclonal to MBD5
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-MBD5 antibody
MBD5 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to MBD5 -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human -
免疫原
Human MBD5
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ポジティブ・コントロール
- human liver lysate, HepG2 cell lysate, transfected 293T cell line
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
バッファー
pH: 7.4
Constituent: PBS -
Concentration information loading...
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精製度
Protein A purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Positive Controls
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab103144の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 160 kDa.
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特記事項 |
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WB
Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 160 kDa. |
ターゲット情報
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機能
Binds to heterochromatin. Does not interact with either methylated or unmethylated DNA (in vitro). -
組織特異性
Detected in heart, placenta, liver, skeletal muscle, kidney and pancreas. -
関連疾患
Defects in MBD5 are the cause of mental retardation autosomal dominant type 1 (MRD1) [MIM:156200]. Mental retardation is characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. -
配列類似性
Contains 1 MBD (methyl-CpG-binding) domain.
Contains 1 PWWP domain. -
ドメイン
Both MBD and PWWP domains are necessary for chromocentric localization. -
細胞内局在
Nucleus. Chromosome. Associated with pericentric heterochromatin and Nucleus. Not associated with pericentric heterochromatin. - Information by UniProt
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参照データベース
- Entrez Gene: 55777 Human
- SwissProt: Q9P267 Human
- Unigene: 458312 Human
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別名
- 9430004D19Rik antibody
- AA536666 antibody
- AI426407 antibody
see all
画像
データシートおよび資料
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Datasheet download
参考文献 (0)
ab103144 は論文での使用が確認できていません。