製品の概要

  • 製品名
    Anti-Matrin 3 antibody [2539C3a]
    Matrin 3 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [2539C3a] to Matrin 3
  • アプリケーション
    適用あり: WB, Dot blotmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant human MATR3 protein.

  • 特記事項

    Abcam is committed to meeting high standards of ethical manufacturing and as such, we will be discontinuing this product, which has been generated by the ascites method, within the next year. We are sorry for any inconvenience this may cause. If you would like help finding an alternative product, please do not hesitate to contact our scientific support team.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab53748 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use at an assay dependent dilution. Predicted molecular weight: 95 kDa.
Dot blot Use at an assay dependent dilution.

ターゲット情報

  • 機能
    May play a role in transcription or may interact with other nuclear matrix proteins to form the internal fibrogranular network. In association with the SFPQ-NONO heteromer may play a role in nuclear retention of defective RNAs.
  • 関連疾患
    Defects in MATR3 are the cause of myopathy distal type 2 (MPD2) [MIM:606070]; also called vocal cord and pharyngeal dysfunction with distal myopathy (VCPDM). MPD2 is a muscular disorder characterized by distal weakness, with onset in hands and feet, associated with vocal cord and pharyngeal weakness causing a nasal voice and swallowing disorders.
  • 配列類似性
    Contains 1 matrin-type zinc finger.
    Contains 2 RRM (RNA recognition motif) domains.
  • 細胞内局在
    Nucleus matrix.
  • Information by UniProt
  • 参照データベース
  • 別名
    • ALS21 antibody
    • KIAA0723 antibody
    • Matr3 antibody
    • MATR3_HUMAN antibody
    • Matrin-3 antibody
    • Matrin3 antibody
    • MPD2 antibody
    • VCPDM antibody
    • Vocal cord and pharyngeal weakness with distal myopathy antibody
    see all

Anti-Matrin 3 antibody [2539C3a] 画像

  • Anti-Matrin 3 antibody [2539C3a] (ab53748) + recombinant immunising protein

    Predicted band size : 95 kDa

プロトコール

Anti-Matrin 3 antibody [2539C3a] (ab53748) 使用論文

This product has been referenced in:
  • Ceballos-Diaz C  et al. Viral expression of ALS-linked ubiquilin-2 mutants causes inclusion pathology and behavioral deficits in mice. Mol Neurodegener 10:25 (2015). Read more (PubMed: 26152284) »
  • Antrobus R  et al. Proteomic analysis of cells in the early stages of herpes simplex virus type-1 infection reveals widespread changes in the host cell proteome. Proteomics 9:3913-27 (2009). Read more (PubMed: 19670248) »

See all 2 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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