The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use at an assay dependent dilution. Predicted molecular weight: 95 kDa.
Use at an assay dependent dilution.
機能May play a role in transcription or may interact with other nuclear matrix proteins to form the internal fibrogranular network. In association with the SFPQ-NONO heteromer may play a role in nuclear retention of defective RNAs.
関連疾患Defects in MATR3 are the cause of myopathy distal type 2 (MPD2) [MIM:606070]; also called vocal cord and pharyngeal dysfunction with distal myopathy (VCPDM). MPD2 is a muscular disorder characterized by distal weakness, with onset in hands and feet, associated with vocal cord and pharyngeal weakness causing a nasal voice and swallowing disorders.
Vocal cord and pharyngeal weakness with distal myopathy antibody
Anti-Matrin 3 antibody [2539C3a] 画像
Western blot - Matrin 3 antibody [2539C3a] (ab53748)
Anti-Matrin 3 antibody [2539C3a] (ab53748) + recombinant immunising protein
Predicted band size : 95 kDa
Anti-Matrin 3 antibody [2539C3a] (ab53748) 使用論文
This product has been referenced in:
Ceballos-Diaz C et al. Viral expression of ALS-linked ubiquilin-2 mutants causes inclusion pathology and behavioral deficits in mice. Mol Neurodegener10:25 (2015).
Read more (PubMed: 26152284) »
Antrobus R et al. Proteomic analysis of cells in the early stages of herpes simplex virus type-1 infection reveals widespread changes in the host cell proteome. Proteomics9:3913-27 (2009).
Read more (PubMed: 19670248) »