製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to MATK - Aminoterminal end
  • アプリケーション
    適用あり: WB, ELISA, IHC-Pmore details
  • 種交差性
    交差種: Mouse, Human
  • 免疫原

    A KLH conjugated synthetic peptide selected from the sequence of Human MATK within amino acids 1-100.

  • ポジティブ・コントロール
    • Mouse thymus tissue lysate, Human hepatocarcinoma tissue.

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • バッファー
    Preservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 精製度
    Protein G purified
  • 特記事項(精製)
    This antibody was purified through a protein G column and eluted out with both high and low pH buffers. It was neutralized immediately after elution, followed by dialysis against PBS.
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab37824 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/100 - 1/500. Detects a band of approximately 56 kDa (predicted molecular weight: 56 kDa).
ELISA 1/1000.
IHC-P 1/50 - 1/100.

ターゲット情報

  • 機能
    Could play a significant role in the signal transduction of hematopoietic cells. May regulate tyrosine kinase activity of SRC-family members in brain by specifically phosphorylating their C-terminal regulatory tyrosine residue which acts as a negative regulatory site. It may play an inhibitory role in the control of T-cell proliferation.
  • 組織特異性
    Expressed in various myeloid cell lines, detected in brain and lung.
  • 配列類似性
    Belongs to the protein kinase superfamily. Tyr protein kinase family. CSK subfamily.
    Contains 1 protein kinase domain.
    Contains 1 SH2 domain.
    Contains 1 SH3 domain.
  • 翻訳後修飾
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 細胞内局在
    Cytoplasm.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CHK antibody
    • Csk homologous kinase antibody
    • Csk type protein tyrosine kinase antibody
    • CTK antibody
    • DKFZp434N1212 antibody
    • EC 2.7.10.2 antibody
    • Hematopoietic consensus tyrosine lacking kinase antibody
    • Hematopoietic consensus tyrosine-lacking kinase antibody
    • HHYLTK antibody
    • Hydroxyaryl protein kinase antibody
    • HYL antibody
    • HYL tyrosine kinase antibody
    • HYLTK antibody
    • Leukocyte carboxyl terminal src kinase related antibody
    • Lsk antibody
    • matK antibody
    • MATK_HUMAN antibody
    • Megakaryocyte associated tyrosine kinase antibody
    • Megakaryocyte associated tyrosine protein kinase antibody
    • Megakaryocyte-associated tyrosine-protein kinase antibody
    • MGC1708 antibody
    • MGC2101 antibody
    • Protein kinase HYL antibody
    • Tyrosine kinase MATK antibody
    • Tyrosine protein kinase CTK antibody
    • Tyrosine-protein kinase CTK antibody
    • Tyrosylprotein kinase antibody
    see all

画像

  • Anti-MATK antibody (ab37824) at 1/100 dilution + Mouse thymus tissue lysate

    Predicted band size : 56 kDa
    Observed band size : 56 kDa
  • ab37824, at a 1/50 dilution, staining MATK in Human hepatocarcinoma by Immunohistochemistry, Formalin fixed and Paraffin embedded tissue. ab37284 was peroxidase-conjugated to the secondary antibody, followed by AEC staining.

    This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

参考文献

ab37824 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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