製品の概要

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab91198 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/2000. Predicted molecular weight: 56 kDa.
ELISA 1/10000.

ターゲット情報

  • 機能
    Could play a significant role in the signal transduction of hematopoietic cells. May regulate tyrosine kinase activity of SRC-family members in brain by specifically phosphorylating their C-terminal regulatory tyrosine residue which acts as a negative regulatory site. It may play an inhibitory role in the control of T-cell proliferation.
  • 組織特異性
    Expressed in various myeloid cell lines, detected in brain and lung.
  • 配列類似性
    Belongs to the protein kinase superfamily. Tyr protein kinase family. CSK subfamily.
    Contains 1 protein kinase domain.
    Contains 1 SH2 domain.
    Contains 1 SH3 domain.
  • 翻訳後修飾
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 細胞内局在
    Cytoplasm.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CHK antibody
    • Csk homologous kinase antibody
    • Csk type protein tyrosine kinase antibody
    • CTK antibody
    • DKFZp434N1212 antibody
    • EC 2.7.10.2 antibody
    • Hematopoietic consensus tyrosine lacking kinase antibody
    • Hematopoietic consensus tyrosine-lacking kinase antibody
    • HHYLTK antibody
    • Hydroxyaryl protein kinase antibody
    • HYL antibody
    • HYL tyrosine kinase antibody
    • HYLTK antibody
    • Leukocyte carboxyl terminal src kinase related antibody
    • Lsk antibody
    • matK antibody
    • MATK_HUMAN antibody
    • Megakaryocyte associated tyrosine kinase antibody
    • Megakaryocyte associated tyrosine protein kinase antibody
    • Megakaryocyte-associated tyrosine-protein kinase antibody
    • MGC1708 antibody
    • MGC2101 antibody
    • Protein kinase HYL antibody
    • Tyrosine kinase MATK antibody
    • Tyrosine protein kinase CTK antibody
    • Tyrosine-protein kinase CTK antibody
    • Tyrosylprotein kinase antibody
    see all

画像

  • Anti-MATK antibody [9D7] (ab91198) at 1/500 dilution + K562 cell lysate

    Predicted band size : 56 kDa

プロトコール

参考文献

ab91198 has not yet been referenced specifically in any publications.

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