Anti-MASS1 抗体 (ab115621)
Key features and details
- Rabbit polyclonal to MASS1
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-MASS1 antibody -
製品の詳細
Rabbit polyclonal to MASS1 -
由来種
Rabbit -
アプリケーション
適用あり: IHC-Pmore details -
種交差性
交差種: Human -
免疫原
Synthetic peptide derived from the N terminal extracellular domain of Human MASS1.
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ポジティブ・コントロール
- Human Brain cortex and Lung (respiratory epithelium) tissues.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at -80°C. -
バッファー
pH: 7.4
Preservative: 0.1% Sodium azide
Constituent: 99% PBS -
Concentration information loading...
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精製度
Protein A purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab115621の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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IHC-P |
Use a concentration of 5 - 10 µg/ml. Formalin-fixed Paraffin-embedded tissues requires pretreatment with Proteinase K.
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特記事項 |
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IHC-P
Use a concentration of 5 - 10 µg/ml. Formalin-fixed Paraffin-embedded tissues requires pretreatment with Proteinase K. |
ターゲット情報
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機能
Receptor that may have an important role in the development of the central nervous system. -
組織特異性
Expressed at low levels in adult tissues. -
関連疾患
Defects in GPR98 are the cause of Usher syndrome type 2C (USH2C) [MIM:605472]. USH is a genetically heterogeneous condition characterized by the association of retinitis pigmentosa with sensorineural deafness. Age at onset and differences in auditory and vestibular function distinguish Usher syndrome type 1 (USH1), Usher syndrome type 2 (USH2) and Usher syndrome type 3 (USH3). USH2 is characterized by congenital mild hearing impairment with normal vestibular responses.
Defects in GPR98 may be a cause of familial febrile convulsions type 4 (FEB4) [MIM:604352]; also known as familial febrile seizures 4. Febrile convulsions are seizures associated with febrile episodes in childhood without any evidence of intracranial infection or defined pathologic or traumatic cause. It is a common condition, affecting 2-5% of children aged 3 months to 5 years. The majority are simple febrile seizures (generally defined as generalized onset, single seizures with a duration of less than 30 minutes). Complex febrile seizures are characterized by focal onset, duration greater than 30 minutes, and/or more than one seizure in a 24 hour period. The likelihood of developing epilepsy following simple febrile seizures is low. Complex febrile seizures are associated with a moderately increased incidence of epilepsy. -
配列類似性
Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
Contains 35 Calx-beta domains.
Contains 6 EAR repeats.
Contains 1 GPS domain. -
発生段階
Isoform 1 is 4 times more abundant than isoform 2 in most tissues tested, despite wide variations in absolute levels of expression. Isoform 3 is expressed at about 1.5 times isoform 1 levels in most tissues examined. In fetal testis, isoform 3 is expressed almost exclusively. -
細胞内局在
Cell membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 84059 Human
- Omim: 602851 Human
- SwissProt: Q8WXG9 Human
- Unigene: 591777 Human
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別名
- DKFZp761P0710 antibody
- FEB 4 antibody
- FEB4 antibody
see all
画像
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab115621 は論文での使用が確認できていません。