製品の概要

  • 製品名Anti-MARK2 antibody
    MARK2 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to MARK2
  • アプリケーション適用あり: WB, IPmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Rabbit, Cow, Dog, Pig, Ferret, Rhesus monkey, Gorilla, Chinese Hamster, Orangutan, Elephant
  • 免疫原

    Synthetic peptide corresponding to a region within amino acids 350-400 of Human MARK2 (NP_001034558.2).

  • ポジティブ・コントロール
    • 293T and Jurkat whole cell lysates

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab113284 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/2000 - 1/10000. Predicted molecular weight: 88 kDa.
IP Use at 2-10 µg/mg of lysate.

ターゲット情報

  • 機能Role in epithelial morphogenesis. Modulates the developmental decision to build a columnar versus a hepatic epithelial cell apparently by promoting a switch from a direct to a transcytotic mode of apical protein delivery. Essential for the asymmetric development of membrane domains of polarized epithelial cells. One or more isoforms may play a role in graft rejection.
  • 組織特異性High levels of expression in heart, brain, skeletal muscle and pancreas, lower levels observed in lung, liver and kidney.
  • 配列類似性Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. MARK subfamily.
    Contains 1 KA1 (kinase-associated) domain.
    Contains 1 protein kinase domain.
    Contains 1 UBA domain.
  • 細胞内局在Cell membrane. Phosphorylated by PRKCZ in polarized epithelial cells, resulting in an interaction with YWHAZ which promotes relocation from the lateral to the apical membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • ELKL motif kinase 1 antibody
    • ELKL motif kinase antibody
    • EMK-1 antibody
    • EMK1 antibody
    • MAP/microtubule affinity regulating kinase 2 antibody
    • MAP/microtubule affinity-regulating kinase 2 antibody
    • Mark2 antibody
    • MARK2_HUMAN antibody
    • MGC99619 antibody
    • PAR 1 antibody
    • Par 1b antibody
    • PAR1 homolog antibody
    • Par1b antibody
    • Ser/Thr protein kinase PAR 1B antibody
    • Serine/threonine protein kinase EMK antibody
    • Serine/threonine protein kinase MARK2 antibody
    • Serine/threonine-protein kinase MARK2 antibody
    see all

Anti-MARK2 antibody 画像

  • All lanes : Anti-MARK2 antibody (ab113284) at 0.1 µg/ml

    Lane 1 : 293T whole cell lysate at 50 µg
    Lane 2 : 293T whole cell lysate at 15 µg
    Lane 3 : 293T whole cell lysate at 5 µg
    Lane 4 : Jurkat whole cell lysate at 50 µg

    Developed using the ECL technique

    Predicted band size : 88 kDa


    Exposure time : 3 minutes
  • ab113284 at 1 µg/ml staining MARK2 in 293T whole cell lysate immunoprecipitated using ab113284 at 6 µg/mg lysate (1 mg/IP; 20% of IP loaded/lane). Lane 2: controle IgG. Predicted band size : 88 kDa. Exposure time: 30 seconds.

Anti-MARK2 antibody (ab113284) 使用論文

ab113284 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab113284.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"