製品の概要

  • 製品名Anti-MARK2 antibody
    MARK2 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to MARK2
  • アプリケーション適用あり: WB, IPmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Dog, Ferret, Rhesus monkey, Gorilla, Orangutan
  • 免疫原

    Synthetic peptide corresponding to a region between amino acids 300 and 350 of Human MARK2 (NP_001034558.2).

  • ポジティブ・コントロール
    • 293T cell lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab113267 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/2000 - 1/10000. Predicted molecular weight: 88 kDa.
IP Use at 2-10 µg/mg of lysate.

ターゲット情報

  • 機能Role in epithelial morphogenesis. Modulates the developmental decision to build a columnar versus a hepatic epithelial cell apparently by promoting a switch from a direct to a transcytotic mode of apical protein delivery. Essential for the asymmetric development of membrane domains of polarized epithelial cells. One or more isoforms may play a role in graft rejection.
  • 組織特異性High levels of expression in heart, brain, skeletal muscle and pancreas, lower levels observed in lung, liver and kidney.
  • 配列類似性Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. MARK subfamily.
    Contains 1 KA1 (kinase-associated) domain.
    Contains 1 protein kinase domain.
    Contains 1 UBA domain.
  • 細胞内局在Cell membrane. Phosphorylated by PRKCZ in polarized epithelial cells, resulting in an interaction with YWHAZ which promotes relocation from the lateral to the apical membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • ELKL motif kinase 1 antibody
    • ELKL motif kinase antibody
    • EMK-1 antibody
    • EMK1 antibody
    • MAP/microtubule affinity regulating kinase 2 antibody
    • MAP/microtubule affinity-regulating kinase 2 antibody
    • Mark2 antibody
    • MARK2_HUMAN antibody
    • MGC99619 antibody
    • PAR 1 antibody
    • Par 1b antibody
    • PAR1 homolog antibody
    • Par1b antibody
    • Ser/Thr protein kinase PAR 1B antibody
    • Serine/threonine protein kinase EMK antibody
    • Serine/threonine protein kinase MARK2 antibody
    • Serine/threonine-protein kinase MARK2 antibody
    see all

Anti-MARK2 antibody 画像

  • 1 mg whole cell lysate from 293T cells was immunoprecipitated using
    Lane 1: ab113267 at 6 µg/mg lysate
    Lane 2: a Rabbit anti-MARK2 antibody that recognizes a downstream epitope
    Lane 3: a control IgG.
    20% of immunoprecipitates was loaded on the gel.
    For WB of immunoprecipitated MARK2, ab113267 was used at 1 µg/ml.
    Detection: Chemiluminescence with an exposure time of 30 seconds.

Anti-MARK2 antibody (ab113267) 使用論文

ab113267 has not yet been referenced specifically in any publications.

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